Sökning: "complete linkage"

Visar resultat 11 - 15 av 39 avhandlingar innehållade orden complete linkage.

  1. 11. Development and application of strategies for the analysis of modification patterns in chondroitin and dermatan sulphate

    Författare :Fang Cheng; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; reumatologi; muskelsystem; Skelett; Glycosaminoglycan; Proteoglycan; Chondroitin sulphate; dermatan sulphate; Sequencing analysis; Modification pattern.; Skeleton; rheumatology locomotion; muscle system; Metabolism; Biokemi; metabolism;

    Sammanfattning : Chondroitin (CS) and dermatan sulphate (DS) are socalled glycosaminoglycans (GAG) that are covalently attached to various type of proteins forming a subgroup within the diverse proteoglycan (PG) family. The PGs studied in this thesis are mostly extracellularly located and include aggrecan, biglycan and decorin. LÄS MER

  3. 12. Psychological and psychiatric aspects in women with disorders of sex development

    Författare :Hedvig Engberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Disorders of sex development (DSD) are an umbrella term for conditions where biological development of sex is affected. Included in this thesis are women with different DSD; women with congenital adrenal hyperplasia (CAH), a disorder causing androgen excess, women with complete androgen insensitivity (CAIS), a disorder of androgen action, and women with complete gonadal dysgenesis (CGD), a complete absence of testicular or ovarian development. LÄS MER

  4. 13. Identification and characterization of candidate genes for type 2 diabetes in the GK rat

    Författare :Hossein Fakhrai-Rad; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Type 2 diabetes is a common multifactorial disorder with complex genetics, which presents with a heterogeneous clinical phenotype as a result of interaction between genetic susceptibility and environmental risk factors. Hence, the search for susceptibility genes for type 2 diabetes in man is difficult. LÄS MER

  5. 14. Från demokrati till e-demokrati : En jämförande studie av demokratiutveckling i det moderna samhället

    Författare :Gustav Lidén; Marie-Louise von Bergmann-Winberg; Katarina Lindblad-Gidlund; Elin Wihlborg; Mittuniversitetet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; e-democracy; democracy; modernization theory; social sustainability; Political science; Statsvetenskap;

    Sammanfattning : This mainly deductive study examines what factors explain the variation of e-democracy and if, why a causal pathway exists. The deductive feature is carried out through examining the predictions of the modernization theory, testing hypotheses concerning the link between economic development and wealth in relation to e-democracy. LÄS MER

  7. 15. Alzheimer's Disease: effect of Tau-related genes on the pathology, neurochemistry and risk of disease

    Författare :Annica Sjölander; Göteborgs universitet; []
    Nyckelord :;

    Sammanfattning : Alzheimer's disease (AD) is the most common form of dementia in the elderly. The predominant sporadic form of AD is a genetically complex disorder probably involving a combination of genetic factors together with environmental influences. To date, the best established genetic risk factor identified is the APOE e4 allele. LÄS MER