Sökning: "complement factor C4."
Visar resultat 1 - 5 av 13 avhandlingar innehållade orden complement factor C4..
1. Crosstalk Between Activated Platelets and the Complement System
Sammanfattning : Several studies have shown that complement and thrombotic events co-exist. Platelets have been suspected to act as the bridge between the two cascade systems. LÄS MER
2. Genetic, molecular and functional analyses of factor I - an inhibitor of the complement system
Sammanfattning : Factor I (FI) is a serine protease that inhibits the complement system by cleaving activated C3 and C4 complement proteins, in the presence of cofactors. Mutations in the gene coding for FI have been identified in complete FI deficient- and atypical hemolytic uremic syndrome (aHUS) patients. LÄS MER
3. Synaptic elimination and the complement system in Alzhaimer's disease
Sammanfattning : The mechanisms behind Alzheimer’s disease (AD) are largely unknown. The disease is to a large extent hereditary, and the best pathophysiological correlate to the severity of the symptoms is loss of synapses. LÄS MER
4. Interactions between platelets and complement with implications for the regulation at surfaces
Sammanfattning : Disturbances of host integrity have the potential to evoke activation of innate immunologic and hemostatic protection mechanisms in blood. Irrespective of whether the activating stimulus is typically immunogenic or thrombotic, it will generally affect both the complement system and platelets to a certain degree. LÄS MER
5. Clinical, epidemiological and immunological aspects of Lyme borreliosis with special focus on the role of the complement system
Sammanfattning : Lyme borreliosis (LB) is the most common vector-borne disease in the Northern Hemisphere. The infection is caused by spirochetes belonging to the Borrelia burgdorferi sensu lato complex, and it is transmitted to humans by ticks. LÄS MER