Sökning: "complement C5b-9"
Visar resultat 1 - 5 av 8 avhandlingar innehållade orden complement C5b-9.
1. Interactions between whole blood and biomaterial surfaces. With focus on the respiratory burst of adhering neutrophils as an early sign of cytotoxicity
Sammanfattning : Although a vast array of materials is used to augment or replace a natural function in the human body, many of them cause side-effects or may be rejected. The growing need for more biocompatible devices has been accompanied by an increase in new materials. LÄS MER
2. NO Effect on Inflammatory Reaction in Extracorporeal Circulation : Ex vivo Studies
Sammanfattning : Nitric oxide (NO) is expressed in inflammatory tissues. However, NO effects are controversial in inflammation; NO is described as acting in a dose dependent manner and possess both pro-inflammatory and anti-inflammatory properties. LÄS MER
3. Studies of the role of complement factor H in hemolytic uremic syndrome
Sammanfattning : Factor H is the main fluid phase regulator of the alternative pathway of complement. Factor H acts as a co-factor for factor I-mediated C3b degradation, inhibits the formation of the C3bBb convertase and accelerates its decay. By discriminating between host and foreign cells, factor H inhibits complement-mediated injury to host cells. LÄS MER
4. Complement-mediated kidney diseases: Genotype, phenotype and inhibition studies
Sammanfattning : Complement-mediated kidney diseases are ultrarare conditions characterized by excess complement activation related in most cases to complement gene variants or circulating autoantibodies. These conditions are chronic and can lead to kidney failure. LÄS MER
5. Pathogenesis of infections related to foreign devices within the cerebral ventricles
Sammanfattning : Coagulase-negative staphyloccoci (CoNS) are the most frequently isolated micro-organisms from infected cerebrospinal fluid (CSF) shunts and temporary ventricular drainage catheters, used in modern neurosurgery. CoNS originate from the skinflora of the patient or the surgeon and gain access to the surface of the implant at the insertion, but the infection can erupt up to a year later or more. LÄS MER