Sökning: "competitive interaction"

Visar resultat 16 - 20 av 141 avhandlingar innehållade orden competitive interaction.

  1. 16. Structural differences in competitive research funding and industry interaction: The case of the Swedish university sector

    Författare :Daniel Ljungberg; Chalmers tekniska högskola; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES;

    Sammanfattning : .... LÄS MER

  3. 17. Uppsalas biotekniska industriella system : En ekonomisk-geografisk studie av interaktion, kunskapsspridning och arbetsmarknadsrörlighet

    Författare :Anders Waxell; Anders Malmberg; Mats Lundmark; Asbjørn Karlsen; Uppsala universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Social and economic geography; Economic geography; biotechnology; industrial clusters; labor market mobility; Uppsala; Sweden; Kulturgeografi; Human geography; Kulturgeografi;

    Sammanfattning : The main purpose of the thesis is to study industrial transformation and growth within a local cluster of biotech activities in Uppsala, Sweden. A combination of theoretical approaches is used to address questions of why certain regions become more competitive: the cluster approach, innovation systems theory, and the technological systems approach. LÄS MER

  4. 18. Interaction kinetic analysis in drug design, enzymology and protein research

    Författare :Vladimir O Talibov; U. Helena Danielson; Glyn Williams; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biokemi; Biochemistry;

    Sammanfattning : The work presented here is focused on the phenomenon of molecular recognition – the mutual ability of biological molecules to recognize each other through their chemical signatures. Here, the kinetic aspects of recognition were evaluated, as interaction kinetics reveal valuable dimensions in the description of molecular events in biological systems. LÄS MER

  5. 19. Electrospray Ionization Mass Spectrometry for Determination of Noncovalent Interactions in Drug Discovery

    Författare :Kurt Benkestock; Johan Roeraade; Renato Zenobi; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mass spectrometry; electrospray ionization; drug discovery; noncovalent interaction; complexes; human serum albumin HSA ; fatty acid binding protein FABP ; ribonuclease; ligand screening; Analytical chemistry; Analytisk kemi;

    Sammanfattning : Noncovalent interactions are involved in many biological processes in which biomolecules bind specifically and reversibly to a partner. Often, proteins do not have a biological activity without the presence of a partner, a ligand. LÄS MER

  7. 20. Computational Modelling of Structures and Ligands of CYP2C9

    Författare :Lovisa Afzelius; Collen Masimirembwa; Ismael Zamora; Anders Karlén; Marcel de Groot; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; CYP2C9; 3D QSAR; GRID; CYP450; pharmacophore modelling; homology modelling; metabolism; competitive inhibitors; CPCA; molecular dynamics simulations; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi; Medicinal Chemistry; läkemedelskemi;

    Sammanfattning : CYP2C9 is one of our major drug metabolising enzymes and belongs to the cytochrome P450 (CYP) super family. The aim of this thesis was to gain an understanding of the quantitative structure–activity relationships (QSAR) of CYP2C9 substrates and inhibitors. LÄS MER