Sökning: "comparative pharmacology"

Hittade 2 avhandlingar innehållade orden comparative pharmacology.

  1. 1. On the use of genomics to asses environmental risks of pharmaceuticals

    Författare :Lina-Maria Gunnarsson; Göteborgs universitet; []
    Nyckelord :comparative pharmacology; ecotoxicology; fish; microarray; genomics; wastewater treatment;

    Sammanfattning : Many drugs are found in the aquatic environment and are therefore a cause for concern. Low concentrations of active ingredients from human pharmaceuticals reach the environment via sewage treatment plants, mainly as a result of excretion. LÄS MER

  2. 2. Tissue-Selective Activation and Toxicity of Substituted Dichlorobenzenes : Studies on the Mechanism of Cell Death in the Olfactory Mucosa

    Författare :Anna Franzén; Eva Brittebo; Ingvar Brandt; Olavi Pelkonen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Toxicology; tissue-selective toxicity; bioactivation; olfactory mucosa; substituted dichlorobenzenes; Bowman s glands; sustentacular cells; ER stress; Grp78; caspase-12; caspase-3; CYP2A5; protein adduction; nasal toxicity; Toxikologi; Toxicology; Toxikologi;

    Sammanfattning : The nasal passages are constantly exposed to both air- and bloodborne foreign compounds. In particular, the olfactory mucosa is demonstrated to be susceptible to a variety of drugs and chemicals. LÄS MER