Sökning: "common insertion site"

Visar resultat 1 - 5 av 16 avhandlingar innehållade orden common insertion site.

  1. 1. The Entheses of the Medial Meniscns and Ligaments of the Knee Joint : Descriptive and Experimental Studies

    Författare :Jizong Gao; Michael Benjamin; Linköpings universitet; []
    Nyckelord :knee joint; meniscus; ligaments; insertion; enthesis; quantitative morphology; fibrocartilage; cement line; collagens; proteoglycans; nerve fibres; tensile strength; failure mode; transection; refixation; repair; healing; osteoarthrosis; histology; immunohistochemistry; biomechanics; rabbit model; MEDICINE; MEDICIN;

    Sammanfattning : Meniscal injuries are common in sports. Surgical removal of the meniscus to relieve symptoms is associated with a high risk for late knee joint osteoarthrosis and pain. Meniscal repair or replacement has therefore been advocated. LÄS MER

  3. 2. Screening for Candidate Brain Tumor Genes : Identifying Genes that Cooperate with Platelet-Derived Growth Factor in Glioma Development and Progression

    Författare :Fredrik Johansson; Bengt Westermark; Leif Carlsson; Uppsala universitet; []
    Nyckelord :Pathology; PDGF; insertional mutagenesis; retroviral tagging; common insertion site; glioma; expression; cGMP-dependent protein kinase II; Patologi;

    Sammanfattning : Malignant primary brain tumors, gliomas, often overexpress both platelet-derived growth factor (PDGF) ligands and receptors providing an autocrine and/or paracrine boost to tumor growth. Glioblastoma multiforme (GBM) is the most frequent glioma. Its aggressive and infiltrative growth renders it extremely difficult to treat. LÄS MER

  4. 3. The structural basis for the catalytic specificity of manganese lipoxygenases : 3D structure analysis of the lipoxygenase of Magnaporthe oryzae

    Författare :Anneli Wennman; Ernst H. Oliw; Marcia Newcomer; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; oxylipin; lipoxygenase; crystal structure; crystallography; HPLC; mass spectrometry; yeast; site-directed mutagenesis; fungi; Biochemical Pharmacology; Biokemisk farmakologi;

    Sammanfattning : Lipoxygenases (LOX) catalyze regio- and stereospecific oxygenation of polyunsaturated fatty acids to hydroperoxides. These hydroperoxides are further metabolized to leukotrienes and lipoxins in mammals, and are involved in asthma and inflammation. LOX of animals and plants contain iron as catalytic metal (FeLOX). LÄS MER

  5. 4. Structure-function studies of plasminogen activator inhibitor-1

    Författare :Guang-Chao Sui; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :PAI-1; site-directed mutagenesis; structure and function; stability;

    Sammanfattning : Plasminogen activator inhibitor-I (PAI-1) is an important physiological inhibitor of tissue-type plasminogen activator (tPA) and urine-type plasminogen activator (uPA). High plasma levels of PAI-1 correlate to thrombotic disease, and low levels can be connected to a bleeding tendency. LÄS MER

  7. 5. Anatomic anterior cruciate ligament reconstruction - current evidence and future directions

    Författare :Kristian Samuelsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anatomic; Anterior Cruciate Ligament; Reconstruction; Score; Level of Evidence;

    Sammanfattning : Injury to the anterior cruciate ligament (ACL) is one of the most common orthopedic diagnoses. It is also one of the most researched areas in orthopedic surgery, with well over eleven thousand publications. LÄS MER