Sökning: "combinatorial coding"
Hittade 4 avhandlingar innehållade orden combinatorial coding.
1. Genetic mechanisms behind cell specification in the Drosophila CNS
Sammanfattning : The human central nervous system (CNS) contains a daunting number of cells and tremendous cellular diversity. A fundamental challenge of developmental neurobiology is to address the questions of how so many different types of neurons and glia can be generated at the precise time and place, making precisely the right connections. LÄS MER
2. Molecular coding and physiological roles of excitatory neurons in motor control
Sammanfattning : Locomotion is a complex motor action that provides humans and other animals with the ability to move through the environment. In vertebrate locomotion, supraspinal centers convey the initiating or terminating command signals to the spinal cord which in turn generates the rhythm and pattern of muscle activities underlying locomotor activity. LÄS MER
3. Genome-wide Studies of Transcriptional Regulation in Yeast
Sammanfattning : In this thesis, nutrient signalling in yeast is used as a model to study several features of gene regulation, such as combinatorial gene regulation, the role of motif context and chromatin modifications. The nutrient signalling system in yeast consists of several pathways that transmit signals about the availability of key nutrients, and regulate the transcription of a large part of the genome. LÄS MER
4. Specification of unique neuronal sub-types by integration of positional and temporal cues
Sammanfattning : The nervous system contains vast numbers of neuronal sub-types, generated at specific time points, in the proper location, and in proper numbers. One of the fundamental issues in neurobiology is to understand the molecular genetic mechanisms that underlie the generation of this daunting neuronal diversity. LÄS MER