Sökning: "colonic microbiota"

Visar resultat 11 - 15 av 20 avhandlingar innehållade orden colonic microbiota.

  1. 11. Microbial regulation of PPARgamma : nuclear receptor networks important for colonic homeostasis

    Författare :Linda Aronsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : One of the central issues surrounding the physiology of good health is to uncover and understand the molecular networks responsible for its maintenance. The alimentary tract in particular, demands a properly sustained homeostatic control since it is constantly challenged by potentially harmful agents along with innocuous nutrients, with the burden of basic metabolic functions in its ward. LÄS MER

  2. 12. Host Immunity-Microbiota-Virus Interactions at the Intestinal Mucosal surface in Health and Disease

    Författare :Kedir Hamza; Virusrekognition; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The presence of viral immune triggers at the intestinal mucosa can have multipleglobal effects on intestinal integrity, including relative protection fromsubsequent inflammatory bowel disease. During the last century, the westernworld has achieved a remarkable success in preventing infectious diseases,which increased the general life expectancy dramatically. LÄS MER

  3. 13. Glycerol esters of butyric and valeric acids counteract diet-related disorders : Prevention of metabolic disturbances induced by high-fat intake

    Författare :Thao Duy Nguyen; Avdelningen för livsmedel och läkemedel; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; short-chain fatty acids; lipid metabolism; cholesterol; gut microbiota; high-fat diet; inflammation; succinic acid; intestinal permeability; tight junction proteins; gut-brain barrier; apolipoprotein E; rats;

    Sammanfattning : Short-chain fatty acids (SCFAs), gut metabolites formed from indigestible dietary components by the colonic microbiota, are associated with numerous health effects, and may be responsible for the beneficial effects, at least in part, associated with dietary fibre. High-fat diets are known to cause low-grade inflammation in the body, but SCFAs are suggested to counteract unfavourable effects induced by these types of diets. LÄS MER

  4. 14. Gastrointestinal Disorders in Women

    Författare :Rita Gustafsson; Gastroenterologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Abstract: This doctoral thesis has sought to clarify the influence of gender in gastrointestinal (GI) disorders. Women with different hormone profiles were investigated, their colonic microbiota was characterized, and the impact of lifestyle and risk factors for GI disease were examined. LÄS MER

  5. 15. Early stage inflammation and cancer as reflected in the gastrointestinal mucus composition: implications for diagnosis, prognosis and pathogenesis

    Författare :Karolina S. Jabbar; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mucus; Mass spectrometry; MUC2; MUC5AC; IPMN; Pancreatic cysts; Ulcerative colitis; IBS; Brachyspira;

    Sammanfattning : Mucus covers our inner interfaces towards the environment, providing protection while enabling vital interaction with the outside world. The mucus is built around mucin proteins, which are important for our defences against infection and inflammation, but may also contribute to carcinogenesis and tumour progression. LÄS MER