Sökning: "collagen diameter"

Visar resultat 1 - 5 av 18 avhandlingar innehållade orden collagen diameter.

  1. 1. Vascular remodelling and circulating basement membrane fragments in abdominal aortic aneurysm

    Författare :Mari Holsti; Malin Sund; Anders Wanhainen; Joakim Nordanstig; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AAA; extracellular matrix; vascular remodelling; collagen; inflammation; Surgery; kirurgi;

    Sammanfattning : An abdominal aortic aneurysm (AAA) is a degenerative disease, characterized by advanced inflammation and extracellular matrix (ECM) remodelling. Enhanced protease activity mediated by cytokines results in the degradation of ECM proteins, leading to the generation of different bioactive fragments. LÄS MER

  3. 2. Regulation of aortic wall mechanics and stress : An experimental study in man

    Författare :Håkan Åstrand; Toste Länne; Matts Karlsson; Martin Björck; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aorta; wall stress; remodeling; IMT; gender; diabetes mellitus; aging; collagen; elastin; Vascular surgery; Kärlkirurgi;

    Sammanfattning : The abdominal aorta (AA) in man is a vulnerable artery prone to atherosclerosis as well as aneurysmatic dilation. The underlying aortic composition, mechanical properties as well as the mechanisms responsible for age-related changes and vascular disease are however largely unknown. LÄS MER

  4. 3. Collagen of the extracellular matrix. Functional and structural studies

    Författare :Olof Olsson; Avdelningen för translationell cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Collagen; Extra Cellular Matrix. TGF-beta; integrin αvβ6;

    Sammanfattning : The cancer microenvironment has been attracting increasing attention as the realization of its importance for both disease treatment and malignant progression. Here the aim was to elucidate some of the effects and mechanisms of the tumor microenvironment related to the extracellular matrix (ECM). LÄS MER

  5. 4. Cartilage Oligomeric Matrix Protein (COMP). Functions in collagen binding and assembly

    Författare :Krisztina Rosenberg; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical biology; Klinisk biologi;

    Sammanfattning : Connective tissues contain a prominent extracellular matrix that provides mechanical and physical properties. This extracellular matrix contains as a major constituent a network of collagen fibres. These are composed of collagen fibrils, which in turn are assembled from many collagen molecules aligned parallel to each other. Several proteins, e. LÄS MER

  7. 5. Stress urinary incontinence in women : pathophysiological aspects

    Författare :Christian Falconer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :menopause; paraurethral connective tissue; extracellular matrix; collagen. proteoglycans; sensory innervation; intravaginal slingplasty.;

    Sammanfattning : Objective: The pathophysiology of female stress urinary incontinence (SUI) is multifactorial. In this thesis biochemical and ultrastructural changes in the paraurethral supporting connective tissue and changes in the innervation of the vaginal wall in relation to SUI have been focused upon. LÄS MER