Sökning: "cohort effect"
Visar resultat 1 - 5 av 841 avhandlingar innehållade orden cohort effect.
1. Birth cohort differences in cognitive aging: Secular trends in cognitive functioning and decline over 30 years in three population-based Swedish samples
Sammanfattning : The overarching aim of this thesis was to investigate birth cohort differences in level of cognitive functioning and change in later life in three population-based representative samples drawn from the Gerontological and Geriatric Population Studies in Gothenburg (H70), Sweden. We used data from cohorts, born in 1901-02, 1906-07, and 1930, measured at ages 70, 75, and 79 on the same cognitive measures. LÄS MER
2. Strategies for assessing health risks from two occupational cohorts within the domain of northern Sweden
Sammanfattning : Background: Studies based on a cohort design requires access to both subject-specific and period-specific information. In order to conduct an occupational cohort study, access to exposure information and the possibility and permission to link information on outcomes from other registers are generally necessary. LÄS MER
3. Prenatal Arsenic Exposure and Consequences for Pregnancy Outcome and Infant Health : Epidemiological Studies in Bangladesh
Sammanfattning : The aim of this thesis was to analyse possible effects of prenatal arsenic exposure on foetal and infant health. The setting is Bangladesh, where two cohorts were studied, both part of a health and demographic surveillance system in Matlab. LÄS MER
4. Epidemiological studies on type 2 diabetes : assessment of diabetes risk factors and study participation
Sammanfattning : Type 2 diabetes is a disease with increasing prevalence. Better knowledge of risk factors may form the bases for specific interventions and preventive measures. The aim of this thesis was to contribute to the knowledge on type 2 diabetes, by examining family history of diabetes and other risk factors with emphasis on psychological exposures. LÄS MER
5. Metabolomics, body composition and fracture
Sammanfattning : In this thesis, I evaluated the impact of pre-centrifugation sample management on the plasma metabolome, providing verification for the protocol used in a study where I applied metabolomics to better understand the role of body composition in fracture occurrence using a large population-based cohort. In paper 1, I applied untargeted liquid chromatography-mass spectrometry (LC-MS) metabolomics analysis to plasma samples (n = 471) from healthy donors to predict and evaluate the effect of pre-centrifugation temperature and delay time on metabolomics data using a combination of random forest and generalized linear models. LÄS MER