Sökning: "cohort analysis"

Visar resultat 1 - 5 av 1040 avhandlingar innehållade orden cohort analysis.

1. 1. Pathway analysis: methods and perspectives

   Författare :Gustavo Stolf Jeuken; Lukas Käll; Mika Gustafsson; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; pathway analysis; mutual information; survival analysis; enrichment analysis; transcriptomics.; Biotechnology; Bioteknologi;

   Sammanfattning : The amount of data being generated by high throughput molecular biology experiments grows every day, both in quantity and quality. With this comes the desire to have more powerful and comprehensive methods for statistical analysis that have been developed with the nature of this data in mind. LÄS MER

3. 2. On Carbohydrate Intake and Dental Status in the Elderly

   Författare :Torgny Alstad; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Carbohydrates; Cohort analysis; Dental caries; Dental status; Elderly; Epidemiology; Factor analysis; Graphic interaction model; Oral sugar clearance;

   Sammanfattning : People?s dental status has the potential to affect dietary intake and, at the same time, diet may affect the health of the dentition. To study the associations, the elderly appear to be an appropriate group and carbohydrates the appropriate nutrients. LÄS MER

4. 3. Epidemiological aspects of drug-related vitamin D deficiency and osteoporotic fractures

   Författare :Ola Nordqvist; Martin Carlsson; Pär Wanby; Thomas Neumark; Björn Wettermark; Linnéuniversitetet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vitamin D; secondary osteoporosis; fractures; drug risk management; medical guideline adherence; electronic health records; real-world data; risk assessment; awareness; attitudes; personalised medicine; cross-sectional study; cohort study; qualitative analysis; thematic analysis; pharmacoepidemiology; Biomedical Sciences; Biomedicinsk vetenskap;

   Sammanfattning : Background: Vitamin D deficiency, secondary osteoporosis and low-energy fractures (LEF) as side effects of specific drugs were first described more than half a century ago. These effects are recognized in guidelines where patients prescribed risk drugs are recommended follow-up with testing and supplementation. LÄS MER

5. 4. Correlated random effects models for clustered survival data

   Författare :Frank Eriksson; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; competing risks; case-cohort; semiparametric; Survival analysis; random effects; routine register; frailty model; Survival analysis; frailty model; competing risks; random effects; case-cohort; routine register; semiparametric;

   Sammanfattning : Frailty models are frequently used to analyse clustered survival data in medical contexts. The frailties, or random effects, are used to model the association between individual survival times within clusters. LÄS MER

7. 5. Proximity Ligation Assays for Disease Biomarkers Analysis

   Författare :Rachel Yuan Nong; Ulf Landegren; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proximity ligation assay; blood biomarkers; protein interactions; pathway analysis; single molecule; next-generation sequencing; Molekylär medicin; Molecular Medicine;

   Sammanfattning : One of the pressing needs in the field of disease biomarker discovery is new technologies that could allow high performance protein analysis in different types of clinical material, such as blood and solid tissues. This thesis includes four approaches that address important limitations of current technologies, thus enabling highly sensitive, specific and parallel protein measurements. LÄS MER