Sökning: "coenzyme Q10"
Hittade 5 avhandlingar innehållade orden coenzyme Q10.
Sammanfattning : Reactive oxygen species (ROS) induce oxidative stress and although are primarily recognized for playing a deleterious biological role, they can be beneficial to cell systems. ROS are extremely short-lived and normally tightly regulated by antioxidant defence systems. LÄS MER
Sammanfattning : Diabetes is closely associated with increased oxidative stress, especially originating from the mitochondria. A mechanism to reduce increased mitochondria superoxide production is to reduce the mitochondria membrane potential by releasing protons across the mitochondria membrane. LÄS MER
Sammanfattning : This thesis presents four studies focusing on outcomes of gait performance using gait analysis and/or the Six-minute-walk test (6MWT), in patients with post-polio syndrome (PPS). Further, resistance training in combination with Coenzyme Q10 (Q10) and intravenous immunoglobulin treatment (IvIg) in PPS patients was evaluated. LÄS MER
4. Translational studies on mitochondrial function and hypoxia in complications of diabetes mellitus
Sammanfattning : Diabetes Mellitus (DM) is a major concern for societies and healthcare systems globally. DMassociated morbidity and mortality is mediated by diabetic complications. Hypoxia and oxidative stress have emerged as key players in the pathogenesis of various macro- and microvascular complications of DM. LÄS MER
Sammanfattning : The transcription factor p53 is one of the most studied tumour suppressors with over 90 000 publications in PubMed referring to the protein. It is also the most frequently mutated gene across all cancer types with around 50% of cancers presenting as mutant p53, and when it is not mutated, it is frequently inactivated to circumvent its tumour suppressor function. LÄS MER