Sökning: "coding repeats"

Visar resultat 16 - 20 av 29 avhandlingar innehållade orden coding repeats.

  1. 16. Antigenic variation in relapsing fever Borrelia

    Författare :Nils Burman; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Borrelia; Relapsing fever; Antigenic variation; Vmp lipoprotein; Rosetting;

    Sammanfattning : The spirochete Borrelia hermsii avoids the immune response of its mammalian host through multiphasic antigenic variation. Serotype specificity is determined by Variable major proteins (Vmp), in the outer membrane. LÄS MER

  3. 17. Functional characterisation of the CAG polymorphism in the androgen receptor- in vitro and in vivo

    Författare :Hannah Nenonen; Diabetes - öpatofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; androgen receptor; polymorphism; CAG polymorphism; androgen receptor activity; infertility; prostate cancer; androgen receptor function;

    Sammanfattning : The androgen receptor (AR) is the mediator of androgen actions. In the AR coding region there is a polymorphic CAG repeat encoding a stretch of the amino acid glutamine (Q). The repeat length modulates receptor activity and is normally distributed between 10-30 CAG with a median length of 22 repeats in white men. LÄS MER

  4. 18. Size matters : RNA silencing processes in Phytophthora infestans

    Författare :Anna Åsman; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Non-coding RNAs do not encode proteins but instead function through their own RNA sequence. These molecules range from several thousands of nucleotides (nt) in length down to around 20 nt. Specifically, small RNAs (sRNAs) have critical functions in eukaryotic cells, despite being only 20-30 nt long. LÄS MER

  5. 19. On 13q14 deletions in chronic lymphocytic leukemia

    Författare :Mikael Lerner; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Malignant tumors arise as a consequence of a multistep process where an accumulation of genetic and epigenetic changes drives the transformation of normal cells into tumor cells. The identification and characterization of genes targeted by these alterations is of crucial importance for an increased understanding of the biology of cancer. LÄS MER

  7. 20. The maintenance of telomeres in the budding yeast Naumovozyma castellii

    Författare :Humberto Itriago; Molekylär cellbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Telomere; Telomere dynamics; Telomere-Binding Proteins; Cdc13; Rap1; RAD52; Rad51; Homologous recombination; ALT; Budding yeast; Naumovozyma castellii;

    Sammanfattning : Linear chromosomes of eukaryotic cells require the presence of functional nucleoprotein terminal structures, known as telomeres, to protect the integrity of the genome. The telomere is a highly dynamic and regulated structure constituted by short tandem DNA repeats rich in guanine nucleotides that extent as double-stranded DNA ending in a single-stranded 3′ overhang. LÄS MER