Sökning: "clinical trials women"

Visar resultat 1 - 5 av 88 avhandlingar innehållade orden clinical trials women.

  1. 1. Female sex hormones and health outcomes in women with specific focus on asthma

    Författare :Guo-Qiang Zhang; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; asthma; Bayesian estimation; case-control; causal inference; estrogens; female sex hormones; hormonal contraceptives; menarche; menopausal hormone therapy; menopause; meta-analysis; multiple imputation; progestogens; research reproducibility; robust variance estimation; systematic review; umbrella review; women;

    Sammanfattning : In humans, gender differences exist across a wide spectrum of diseases. For instance, women are more likely to develop Sjogren’s syndrome, systemic lupus erythematosus, and autoimmune thyroid disease compared to men. LÄS MER

  3. 2. Women's hearts : ischaemic heart disease and stress management in women

    Författare :Maria Claesson; Kjell Asplund; Gunilla Burell; Cecilia Mattsson; Annika Rosengren; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; ischaemic heart disease; women; cognitive-behavioural therapy; psychosocial risk factors; inflammation; leptin; haemostasis; fibrinolysis; insulin resistance; HRV; ischemic heart disease; cognitive behavioral therapy; heart rate variability; chd; cvd; cad; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; medicin; Medicine;

    Sammanfattning : Acute myocardial infarction (AMI), caused by ischaemic heart disease (IHD), is a leading cause of death in both men and women in the western society. Hypertension, diabetes, and smoking are examples of well-known risk factors of IHD, but also there are psychosocial factors, such as stress, vital exhaustion (unusual fatigue, irritability, and demoralization) and depression that have been associated with an increased risk in both genders. LÄS MER

  4. 3. Bridging the gap between clinical trials and clinical practice : sacubitril-valsartan in heart failure as a model

    Författare :Helena Norberg; Krister Lindmark; Ellinor Bergdahl; Eva-Lotta Glader; Björn Wettermark; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systematic implementation; healthcare quality improvement; chronic disease management; heart failure; sacubitril-valsartan; real-world population; sex differences; kardiologi; Cardiology;

    Sammanfattning : When novel treatments prove more effective than standard therapies, a swift and effective implementation is needed to reach cost-effectiveness and to benefit eligible patients. Meanwhile, women and elderly are often under-represented in clinical trials, which creates a knowledge gap on how to optimize treatment in clinical practice. LÄS MER

  5. 4. Recurrent stroke : risk factors, predictors and prognosis

    Författare :Johanna Pennlert; Marie Eriksson; Per-Gunnar Wiklund; Bo Carlberg; Hélène Pessah-Rasmussen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; stroke; risk factors; atrial fibrillation; anticoagulant; antiplatelet; intracerebral hemorrhage; stroke recurrence; socioeconomic status; medicin; Medicine;

    Sammanfattning : Background Many risk factors for stroke are well characterized and might, at least to some extent, be similar for first-ever stroke and for recurrent stroke events. However, previous studies have shown heterogeneous results on predictors and rates of stroke recurrence. LÄS MER

  7. 5. MAPK and pro-inflammatory mediators in the walls of brain blood vessels following cerebral ischemia

    Författare :Aida Maddahi; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mitogen activated protein kinase; iNOS; Matrix metalloproteinases; IL-1ß; IL-6; TNF-α; Inflammation; Subarachnoid hemorrhage; Middle cerebral artery occlusion;

    Sammanfattning : INTRODUCTION Stroke is a serious neurological disease which may lead to death and severe disability [1, 2]. There are two major types of stroke: ischemic and hemorrhagic stroke. LÄS MER