Sökning: "cleaning-in-place"

Hittade 2 avhandlingar innehållade ordet cleaning-in-place.

1. 1. Engineering Proteinaceous Ligands for Improved Performance in Affinity Chromatography Applications

   Författare :Susanne Gülich; KTH; []
   Nyckelord :affinity chromatography; cleaning-in-place; deamidation; destabilization; linker engineering; protein engineering; stabilization; staphylococcal protein A; streptococcal protein G; turn loop engineering;

   Sammanfattning : .... LÄS MER

3. 2. Protein engineering to explore and improve affinity ligands

   Författare :Martin Linhult; KTH; []
   Nyckelord :binding; affinity; human serum albumin HSA ; albumin-binding domain ABD ; affinity chromatography; deamidation; protein A; stabilization; Z-domain; capacity; protein G; cleaning-in-place CIP ; protein engineering; C2 receptor;

   Sammanfattning : In order to produce predictable and robust systems forprotein purification and detection, well characterized, small,folded domains descending from bacterial receptors have beenused. These bacterial receptors, staphylococcal protein A (SPA)and streptococcal protein G (SPG), possess high affinity to IgGand / or HSA. LÄS MER