Sökning: "class differentiation"

Visar resultat 16 - 20 av 116 avhandlingar innehållade orden class differentiation.

  1. 16. Long non-coding RNAs in the epigenetic regulation of oligodendrocyte differentiation

    Författare :Samudyata Samudyata; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Long non-coding RNAs (lncRNAs) constitute a heterogeneous class of RNAs with limited coding potential, united by an arbitrarily placed cut off of >200 ntd. The past decade has seen the emergence of lncRNAs as versatile regulators of gene expression, amidst skepticism regarding the biological usefulness of pervasive genomic transcription and its non-coding RNA products prevalent in most eukaryotes. LÄS MER

  3. 17. Impairment of B cell trafficking and differentiation during HIV-1 infection

    Författare :Vu Phuong Linh Dang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : During the course of HIV-1 infection, several B cell dysfunctions occur as result of virus replication and indirect mechanisms of immunopathology. The B cells abnormalities include hypergammaglobulinemia, a decreased number of memory B cells, increased levels of activation markers on B cell surface and plasmacytosis. LÄS MER

  4. 18. In vitro studies on human first trimester forebrain cells : differentiation and interactions with immunoregulating molecules

    Författare :Alyaa Mohammed Ali Mousa; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This thesis has focused on understanding, at the molecular level, growth regulation and differentiation of human first trimester forebrain cells, and the immune signals mediating these processes. Primary cultures were established from human forebrain tissue derived from elective first trimester abortions. LÄS MER

  5. 19. Regulation of B cell development by antigen receptors

    Författare :Jannek Hauser; Thomas Grundström; Yuan Zhuang; Umeå universitet; []
    Nyckelord :calcium; calmodulin; e-proteins; E2A; B cell development; antigen receptor signaling; surrogate light chains; RAG; allelic exclusion; V D J recombination; AID; negative feedback regulation; plasma cell differentiation;

    Sammanfattning : The developmental processes of lymphopoiesis generate mature B lymphocytes from hematopoietic stem cells through increasingly restricted intermediates. Networks of transcription factors regulate these cell fate choices and are composed of both ubiquitously expressed and B lineage-specific factors. LÄS MER

  7. 20. MHC and genomic diversity in Atlantic salmon (Salmo salar L.)

    Författare :Jakob Lohm; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Djurekologi; cytogenetik; Genetik; cytogenetics; Genetics; nucleotide diversity; isolation-by-distance; DGGE; AFLP; furunculosis; disease resistance; Arctic charr; brown trout; Atlantic salmon; population genetics; genetic variation; Mhc class IIB; Animal ecology;

    Sammanfattning : In this thesis I present studies concerning genomic diversity and genetic heterogeneity as well as the evolution and maintenance of genetic variation at a specific immune defence gene in Atlantic salmon (Salmo salar, L.). LÄS MER