Sökning: "clamp"
Visar resultat 11 - 15 av 180 avhandlingar innehållade ordet clamp.
11. Electrophysiology of pancreatic A-, B- and D-cells studied in intact mouse islets of Langerhans
Sammanfattning : Abstract The electrophysiological properties of insulin-secreting b-cells, glucagon-releasing a-cells and somatostation-producing d-cells in intact mouse pancreatic islets were investigated using the perforated patch whole-cell technique. It is demonstrated that it is possible to functionally identify the different cell types in situ. LÄS MER
12. Calcium channel activity and force regulation in smooth muscle: Effects of polyamines and growth stimulation
Sammanfattning : The initial signal for contraction in smooth muscle is an increase in [Ca2+]i. Ca2+ ions can either enter the cytosol from the extracellular medium or be released from intracellular stores. Voltage-operated Ca2+ channels (VOC) play a dominant role in the activation of smooth muscle contraction. LÄS MER
13. On methods for probing structure and function of membrane proteins
Sammanfattning : The determination of structure–function relationships in membrane proteins plays a key role for the understanding of molecular mechanisms in biological systems, and may provide information on how these systems can be modulated by pharmaceuticals. The aim of the work described herein was to develop methods for studying structure and function of membrane proteins, ideally in combination. LÄS MER
14. The Best Leading Role for Maintaining Normal β-cell Function Goes to MafA and Voltage-gated Calcium Channel Subunit γ4
Sammanfattning : .... LÄS MER
15. Thermo- and chemosensitive properties of Transient Receptor Potential Ankyrin 1 ion channels
Sammanfattning : The ability to sense and accommodate to an ever-changing environment is crucial for the survival of living organisms. Transient Receptor Potential (TRP) ion channels comprise a large superfamily of cation conducting membrane proteins that function as molecular sensors in diverse sensory processes including perception of light, taste, smell, sound, touch and temperature. LÄS MER