Sökning: "ciita"
Visar resultat 1 - 5 av 11 avhandlingar innehållade ordet ciita.
1. Functional genetics of the interleukin-4 receptors in allergic asthma
Sammanfattning : Asthma is a complex disorder, with both genetic and environmental factors contributing to disease development. Our aim was to analyse possible associations between genetic variations of immunologically important genes and the susceptibility to and severity of allergic asthma in adults. LÄS MER
2. Dynamics of Human Leukocyte Antigen-D Related expression in bacteremic sepsis
Sammanfattning : Monocytic human leukocyte antigen-D related (mHLA-DR) expression determined by flow cytometry has been suggested as a biomarker of sepsisinduced immunosuppression.In order to facilitate use of HLA-DR in clinical practice, a quantitative real-time PCR technique measuring HLA-DR at the transcription level was developed and evalutated. LÄS MER
3. Genetic studies of non-HLA loci in rheumatoid arthritis : expression and interaction of candidate genes
Sammanfattning : Genetic predisposition is an important contributor in development of human complex diseases, like rheumatoid arthritis (RA). In this thesis work, we present advances for involvement of non-HLA genetic risk factors for RA. LÄS MER
4. Genetic analysis of candidate susceptibility genes for type 1 diabetes
Sammanfattning : Type 1 diabetes (T1D) is a complex disease where the pancreatic β-cells are destroyed in an autoimmune attack. For the patients, this leads to lifelong daily insulin treatment and increased risk for various kinds of complications. It is thought that both environmental as well as genetic factors act in concert to cause T1D. LÄS MER
5. Genetic studies of complex autoimmune disease
Sammanfattning : In complex autoimmune diseases, there are both genetic and environmental factors that influence our immune system and contribute to the development of disease. The pathways, interactions and mode of inheritance are difficult to unravel, and many discoveries are yet to be done. LÄS MER