Sökning: "chronic graft dysfunction"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden chronic graft dysfunction.

1. 1. Mechanisms and treatment options of chronic graft dysfunction : Experimental and clinical studies

   Författare :Lilija Zezina; Uppsala universitet; []
   Nyckelord :Medical sciences; chronic graft dysfunction; kidney transplantation; aorta transplantation; lipid oxidation; LDL; TGF-beta; Smad2; angiotensin II receptor; treatment; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

   Sammanfattning : Chronic graft dysfunction (CGD) is an important post-transplant complication. CGD can be considered as an impaired repair process, which ultimately leads to the loss of graft function.To study non-immunological factors contributing to the development of CGD in kidney grafts we used in vitro and in vivo models, and clinical studies. LÄS MER

3. 2. Female genital Graft-versus-Host Disease - Diagnosis, Treatment, Incidence, Long-term Prevalence, and Impact on Androgen Hormones and Sexual Function

   Författare :Eva Smith Knutsson; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allogeneic stem cell transplantation; chronic graft-versus-host disease; female genitalia; diagnostic; treatment; androgens in women; glucocorticosteroids; sexual dysfunction;

   Sammanfattning : ABSTRACT BACKGROUND. Chronic graft-versus-host disease (cGvHD) is the major cause of morbidity after allogeneic hematopoietic stem cell transplantation (alloSCT), and contributes to non-relapse mortality. Caused by donor cells, cGvHD is a multi-organ syndrome involving tissue inflammation and fibrosis. AIMS. LÄS MER

4. 3. Lower urinary tract dysfunction in children with chronic kidney disease : before an after renal transplantation

   Författare :Helena Öborn; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Chronic kidney disease (CKD) in children is a complex condition with the risk of progression to end-stage renal disease (ESRD) requiring dialysis or renal transplantation. Children with CKD and pediatric renal transplant recipients face a variety of complications, such as side effects of the treatment and concerns about deterioration of graft function. LÄS MER

5. 4. The clinical importance of anti-endothelial cell antibodies in chronic kidney dysfunction and organ transplantation

   Författare :Nidia Maritza Hernandez; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endothelial Cells; Anti-endothelial cell antibodies; Organ Rejection; Tissue Engineering;

   Sammanfattning : The endothelium is the thin layer of cells that lines the interior surface of blood vessels and is the first site of contact between immune cells and tissues. Therefore, alterations at the level of the endothelium are crucial to understand the nature of vascular diseases and organ damage. LÄS MER

7. 5. Cytomegalovirus infection in vascular diseases and transplant rejection

   Författare :Mensur Dzabic; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Human cytomegalovirus (HCMV) infects 60-100% of the adult population. It belongs to the Herpesviridae family and establishes latency within its host post primary infection. HCMV reactivation is dependent on inflammation and the virus has evolved numerous mechanisms to sustain an inflammatory process and thus prolong its replication period. LÄS MER