Sökning: "chromosome interactions"
Visar resultat 1 - 5 av 66 avhandlingar innehållade orden chromosome interactions.
1. Genetic Variations in Type 2 Diabetes and Cardiovascular Disease: A Focus on Gene-Lifestyle Interactions and Mendelian Randomization
Sammanfattning : Type 2 diabetes (T2D) and cardiovascular disease (CVD) are highly prevalent complex diseases that result from lifestyle and genetic factors. Gene-lifestyle interactions are also believed to contribute to the etiology of these diseases. LÄS MER
2. The Control of the Epigenome
Sammanfattning : The genetic information required for the existence of a living cell of any kind is encoded in the sequence information scripted in the double helix DNA. A modern trend in biology struggles to come to grip with the amazing fact that there are so many different cell types in our body and that they are directed from the same genomic blueprint. LÄS MER
3. The role of hematopoietic chromosome Y loss in health and disease
Sammanfattning : Mosaic loss of chromosome Y (mLOY) is the most common somatic mutation, and affected men have increased risk for all major causes of death, including cardiovascular diseases and cancer. As a male specific mutation, it helps explain why men live shorter lives than women. LÄS MER
4. Meiotic chromosome segregation : molecular analysis of the synaptonemal complex
Sammanfattning : Meiosis is a special type of cell division that produces haploid gametes from diploid parental cells. As such, meiosis stands at the gateway to sexual reproduction in most eukaryotic organisms. During meiosis, a complex, but tightly coordinated series of events occur. Homologous chromosomes come together and pair along their entire length. LÄS MER
5. Nuclear envelope protein interaction studies
Sammanfattning : The nuclear envelope (NE) separating the nucleoplasm from cytoplasm consists of two concentric lipid membranes, the outer (ONM) and inner (INM) nuclear membranes, the nuclear pore complexes (NPCs) and an underlying nuclear lamina network. The INM contains more than 100 unique transmembrane proteins of which only a few have been characterized. LÄS MER