Sökning: "chromosome 6"

Visar resultat 6 - 10 av 281 avhandlingar innehållade orden chromosome 6.

  1. 6. The Smc5/6 complex : linking DNA replication with chromosome segregation

    Författare :Kristian Jeppsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In order to faithfully propagate the genetic material from one generation to the next, cells need to properly replicate and segregate their chromosomes. The three well-conserved eukaryotic Structural Maintenance of Chromosomes (SMC) protein complexes, cohesin, condensin and the Smc5/6 complex (Smc5/6) organize chromosomes to ensure that the daughter cells receive a full complement of chromosomes. LÄS MER

  3. 7. Identification and Characterization of Novel Candidate Oncogenes

    Författare :Marina Mencinger; Avdelningen för klinisk genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk genetik; Clinical genetics; RBP56; APRIL; TFG; FUS; EWS; EST database; fusion genes; chromosome; molecular genetics; cancer; Cytology; oncology; cancerology; Cytologi; onkologi;

    Sammanfattning : Using computer-assisted sequence homology searches we identified three genes encoding proteins similar to certain fusion partner proteins in cancer. The novel APRIL gene was localized to 15q25 and encodes a protein, containing an acidic amino-acid region similar to that/those of leukemia-associated fusion partner proteins DEK and SET. LÄS MER

  4. 8. Evolution of sex chromosomes in Sylvioidea songbirds

    Författare :Hanna Sigeman; MEMEG; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Sex chromosome; neo-sex chromosome; Birds; vertebrates; Genomics; Bioinformatics;

    Sammanfattning : Sex chromosomes were discovered more than 100 years ago. They have been studied intensely from a theoretical perspective since then, giving rise to a large body of testable predictions about their evolution from autosomes. LÄS MER

  5. 9. Looking for arthritis regulating genes on mouse chromosome 6 & 14

    Författare :Marjan Popovic; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Rheumatoid arthritis (RA) is a chronic autoimmune disease of the joints with a complex aetiology affected by largely unknown genetic and environmental factors. Since ~60% of susceptibility to RA is genetically inherited, one way to progress towards understanding of the disease is to identify the disease regulating genes. LÄS MER

  7. 10. On multi body systems simulation in product design

    Författare :Petri Makkonen; KTH; []
    Nyckelord :;

    Sammanfattning : The aim of this thesis is to provide a basis for efficientmodelling and software use in simulation driven productdevelopment. The capabilities of modern commercial computersoftware for design are analysed experimentally andqualitatively. LÄS MER