Sökning: "chromosome 6"

Visar resultat 1 - 5 av 239 avhandlingar innehållade orden chromosome 6.

  1. 1. Molecular mechanisms in cervical carcinogenesis : Studies of clonality, somatic genetic alterations and human papillomavirus variants in cervical pre-invasive and invasive cancer

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Zhongmin Guo; Uppsala universitet.; [2000]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; cervical cancer; CIN; clonality; X-chromosome inactivation; LOH; HPV; chromosome 3p; chromosome 6; Genetik; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Clinical genetics; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Klinisk genetik; Pathology; patologi;

    Sammanfattning : Cervical cancer derives from a series of pre-invasive cervical neoplastic lesions termed CIN I-III (Cervical Intraepithelial Neoplasia) via typical multiple-step processes. In contrast to premalignant disorders in other organs, different degrees of CIN possess a distinct biological behaviour where a proportion spontaneously regress or persist, whereas some progress to invasive cancer. LÄS MER

  2. 2. Analysis of the origin and spread of the domestic dog using Y-chromosome DNA and mtDNA sequence data

    Detta är en avhandling från Stockholm : KTH Royal Institute of Technology

    Författare :Mattias Oskarsson; KTH.; [2012]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; mtDNA; domestication; Y-chromosome; SNP; ASY; dog; dingo;

    Sammanfattning : The domestic dog was probably the first domesticated animal, and the only one to spread to all continents in ancient times. The dog is one of the most phenotypically diverse animals, a result of human selection throughout dog history. LÄS MER

  3. 3. Development and Application of Human Chromosome 22 Genomic Microarray Chromosome 22-Associated Disorders Analyzed by Array-Based Comparative Genomic Hybridization

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Magdalena Benetkiewicz; Uppsala universitet.; [2006]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; DNA copy number changes; chromosome 22; genomic microarray; array-CGH; schwannoma; neurofibromatosis type 2; ovarian carcinoma; breast cancer; Wilms tumor; Genetik; NATURAL SCIENCES Biology Cell and molecular biology Genetics; NATURVETENSKAP Biologi Cell- och molekylärbiologi Genetik;

    Sammanfattning : The array-based form of comparative genomic hybridization (array-CGH) is a new methodology that has shown to be of significant importance. This thesis focuses on the development of array-CGH with the aim to define candidate regions/genes on chromosome 22 in a wide spectrum of cancer-related conditions. LÄS MER

  4. 4. Characterization of chromosome abnormalities

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Molecular Medicine and Surgery

    Författare :Anna Lindstrand; Karolinska Institutet.; Karolinska Institutet.; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Inborn chromosome abnormalities are a frequent cause of mental retardation and birth defects. Apart from aberrations that are visible in the microscope, a number of submicroscopic alterations have recently been discovered, and all of these chromosome changes are in fact the result of DNA alterations at the molecular level. LÄS MER

  5. 5. The smc5/6 complex : linking DNA replication with chromosome segregation

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Cell and Molecular Biology

    Författare :Kristian Jeppsson; Karolinska Institutet.; Karolinska Institutet.; [2015]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : In order to faithfully propagate the genetic material from one generation to the next, cells need to properly replicate and segregate their chromosomes. The three well-conserved eukaryotic Structural Maintenance of Chromosomes (SMC) protein complexes, cohesin, condensin and the Smc5/6 complex (Smc5/6) organize chromosomes to ensure that the daughter cells receive a full complement of chromosomes. LÄS MER