Sökning: "choroid"

Visar resultat 1 - 5 av 39 avhandlingar innehållade ordet choroid.

  1. 1. α1- and α2-Adrenoceptors in the Eye : Pharmacological and Functional Characterization

    Författare :Anna Wikberg-Matsson; Thomas Mittag; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; α1-adrenoceptor subtypes; α2-adrenoceptor subtypes; iris; ciliary body; choroid; retina; ciliary artery; Neurovetenskap; Neurology; Neurologi; Ophtalmology; oftalmiatrik;

    Sammanfattning : α1- and α2-Adrenoceptors are involved in various physiological events in the eye: blood flow regulation, aqueous humor dynamics and pupil regulation. The α1- and α2-adrenoceptors can be further subdivided into six subtypes (α1A, α1B, α1D, α2A , α2B, and α2C ). LÄS MER

  3. 2. Signaling to the immature brain - Choroid plexus, insulin-like growth factor 1 and extracellular vesicles

    Författare :Niklas Ortenlöf; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IGF-1; Choroid plexus; Immature brain; Extracellular vesicle; CSF; Preterm infants;

    Sammanfattning : Extremely preterm infants (i.e., born below 28 gestational weeks), are at high risk of developing brain morbidities including intraventricular hemorrhage (IVH) and neurodevelopmental impairment. Despite over 50 years of research, there is currently no effective therapy available for preventing IVH. LÄS MER

  4. 3. Interactions between neural retina, retinal epithelium and choroid

    Författare :Lena Ivert; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :RPE; neural retina; basal lamina; Bruch s membrane; choroid; subretinal space; bleb detachment; ICG; FAG; SLO; choroidal blood flow.;

    Sammanfattning : The retinal pigment epithelium (RPE) is a non-replicating monolayer that plays a key role nursing the photoreceptors of the neural retina, regulating fluid movement within the subretinal space, maintaining a basal laminar layer of Bruch s membrane, and influencing the choriocapillaris. This project investigates how surgical manipulation of the retinal epithelial layer influences the neural retina, the choroid and the epithelial layer itself. LÄS MER

  5. 4. Developing brain and systemic inflammation: a "Toll-like" link with consequences

    Författare :Amin Mottahedin; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; developing brain; neonatal brain injury; hypoxia-ischemia; inflammation; infection; Toll-like receptor; choroid plexus; neuroimmunology; Mitochondria;

    Sammanfattning : The developing brain is vulnerable to external insults, and perinatal brain injury (PBI) is a major cause of life-long neurological syndromes such as cerebral palsy. Currently, no pharmaceutical intervention is available. Hypoxia/ischemia (HI), infections and inflammation are implicated in the pathogenesis of PBI. LÄS MER

  7. 5. Spatial and temporal regulation of neural stem cells in the developing brain by PRDM16

    Författare :Li He; Qi Dai; Christos Samakovlis; Simon Hippenmeyer; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brain development; Neural stem cell; PRDM16; BMP signaling; Choroid plexus; Cortical neurogenesis; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : The mammalian brain comprises a large number and diversity of neurons and non-neural cells. Most of these cell types derive from a single sheet of neuroepithelium (NE) that contains a limited pool of neural stem cells (NSCs).  NSCs in the developing brain are under complex regulation to achieve maximum daughter cell type diversity. LÄS MER