Sökning: "cholesterol hypersecretion"

Hittade 2 avhandlingar innehållade orden cholesterol hypersecretion.

  1. 1. Studies of sterol 12alpha-hydroxylase (CYP8B1) : distribution and role for cholesterol homeostasis and gallstone formation

    Författare :Jin Wang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :CYP8B1; CY7P7A1; bile acid; cholesterol homeostasis; gallstone; nuclear receptor; cellular distribution; cholesterol hypersecretion; ABCG5 G8; SREBP2; cholesterol absorption; diabetes mellitus; anti-atherogenesis;

    Sammanfattning : Bile acids are essential physiological molecules which carry out multiple functions such as facilitating the absorption of dietary lipids and regulating the metabolism of cholesterol and bile acids. The formation of bile represents the major route for elimination of excess cholesterol, either by conversion of cholesterol into bile acids or excretion of intact cholesterol in mixed micelles. LÄS MER

  3. 2. Gallstone disease in a Swedish population : an epidemiological investigation

    Författare :Olle Muhrbeck; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cholelithiasis; cholecystectomy; cholesterol; epidemiologySweden; incidence; lathosterol; mass screening; prevalence; risk factors; symptoms; ultrasonography; 7-a-hydroxy-4-cholesten-3-one;

    Sammanfattning : The main objective of the present thesis was to study the prevalence of gallstone disease in a community survey in Danderyd. Symptoms and risk factors for gallstone disease and the changing incidence of cholecystectomy in Stockholm County was also studied. LÄS MER