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Visar resultat 1 - 5 av 16 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Cholangiocarcinoma in primary sclerosing cholangitis

    Författare :Annika Bergquist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Primary sclerosing cholangitis; pancreatic carcinoma; cholangiocarcinoma; ulcerative colitis; biliary dysplasia; apoptosis; Ki-67; p53; bcl-2.;

    Sammanfattning : Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown causes closely associated with ulcerative colitis. PSC is a progressive disease leading to liver failure and need for liver transplantation. Cholangiocarcinoma (CC) occurs in 10-20% of patients with PSC. LÄS MER

  2. 2. Distal cholangiocarcinoma - from novel biomarkers to clinical management and outcome

    Författare :Johannes Byrling; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Distal cholangiocarcinoma; biliary tract cancer; periampullary cancer; pancreatoduodenectomy; lymph node metastasis; stroma; SPARC; THBS2; biomarker; mass spectrometry; Diagnosis; histopathology;

    Sammanfattning : Cholangiocarcinoma is an aggressive malignacy arising from the biliary tree. Anatomical subtypes ofcholangiocarcinoma differs in tumor biology and clinical management. Distal cholangiocarcinoma (dCCA)originates from the common bile duct. LÄS MER

  3. 3. Chemoradiation in Gastrointestinal Cancer

    Författare :Adalsteinn Gunnlaugsson; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biliary tract cancer; capecitabine; cholangiocarcinoma; chemoradiation; colon cancer; enteritis 5-fluorouracil; gallbladder cancer; oxaliplatin; pancreatic cancer; rectal cancer.;

    Sammanfattning : Locally advanced inextirpable gastrointestinal cancer has poor prognosis and is associated with high morbidity. One treatment option is to use radiotherapy, often combined with chemotherapy (chemoradiation), either as preoperative treatment to facilitate surgery or in the palliative setting to relieve symptoms. LÄS MER

  4. 4. Diagnostic and prognostic value of the AST/ALT ratio as an indicator of cirrhosis in chronic liver disease

    Författare :Helena Nyblom; Göteborgs universitet; []
    Nyckelord :alcohol dependence; alcohol-related liver disease; AST ALT ratio; cirrhosis; cholangiocarcinoma; primary biliary cirrhosis; primary sclerosing cholangitis;

    Sammanfattning : .... LÄS MER

  5. 5. Endoscopic methods for detecting malignancy in patients with ulcerative colitis and primary sclerosing cholangitis

    Författare :Bo Lindberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Ulcerative colitis; primary sclerosing cholangitis; cholangiocarcinoma; colorectal cancer; dysplasia; brush cytology; Endoscopic Retrograde Cholangiopancreatography ERCP .;

    Sammanfattning : Ulcerative colitis (UC) is a chronic ulcerative inflammatory bowel disease affecting the mucosa of the large intestine. UC patients have an increased risk for the development of colorectal cancer mainly associated with long duration and extensive involvement of the colitis. LÄS MER