Sökning: "chitin synthase"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden chitin synthase.

  1. 1. Identification and characterisation of chitin and cellulose synthases in oomycetes : New tools for biochemical studies and structure determination

    Författare :Stefan Klinter; Vincent Bulone; Lauren S. McKee; Mirjam Czjzek; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; biochemical characterisation; cellulose synthase; chitin synthase; in vitro activity assay; microtubule-interacting and trafficking domain; nanoparticle; oomycetes; phylogenetic analysis; yeast engineering; biokemisk karakterisering; cellulosasyntas; kitinsyntas; in vitro aktivitetsanalys; mikrotubulus-interagerande och -trafikerande domän; nanopartikel; oomyceter; fylogenetisk analys; jäst proteinteknik; Bioteknologi; Biotechnology;

    Sammanfattning : Despite resembling ‘true’ fungi in terms of morphological features, oo­mycetes form a distinct eukaryotic lineage of filamentous microorganisms that belongs to the stramenopiles, a group of protists also comprising the closely-related brown algae and diatoms. Many oomycetes are devastating pathogens of plants and animals, globally causing significant economic los­ses in the agriculture and aquaculture industries, and posing considerable environmental damage to natural ecosystems. LÄS MER

  2. 2. Genetic and molecular regulation of epithelial tube morphogenesis

    Författare :Anna Tonning; Göteborgs universitet; []
    Nyckelord :epithelial tube morphogenesis; trachea; Drosophila; chitin; chitin synthase; apical extracellular matrix; paracellular diffusion barrier; tube expansion; septate junctions;

    Sammanfattning : Networks of epithelial tubes, such as the vertebrate lung, kidney and vascular system, enable transport of gases and nutrients to all tissues in the body. These tubes are built up by a single layer of polarized epithelial cells, with the apical membrane facing the lumen. LÄS MER

  3. 3. Functional characterization of cellulose and chitin synthase genes in Oomycetes

    Författare :Johanna Fugelstad; Vincent Bulone; Carol Munro; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cellulose biosynthesis; chitin biosynthesis; cellulose synthase gene; chitin synthase gene; Oomycetes; Phytophthora infestans; Saprolegnia monoica; pleckstrin homology domain; Microbiology; Mikrobiologi;

    Sammanfattning : Some species of Oomycetes are well studied pathogens that cause considerable economical losses in the agriculture and aquaculture industries. Currently, there are no chemicals available that are environmentally friendly and at the same time efficient Oomycete inhibitors. LÄS MER

  4. 4. Structure and lipid interactions of membrane-associated glycosyltransferases : Cationic patches and anionic lipids regulate biomembrane binding of both GT-A and GT-B enzymes

    Författare :Scarlett Szpryngiel; Lena Mäler; Marcelo Guerins; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; glycosyltransferase; monotopic membrane proteins; galactolipids; NMR; chitin synthase; DGD2; LPS; WaaG; MIT domain; Biophysics; biofysik;

    Sammanfattning : This thesis concerns work on structure and membrane interactions of enzymes involved in lipid synthesis, biomembrane and cell wall regulation and cell defense processes. These proteins, known as glycosyltransferases (GTs), are involved in the transfer of sugar moieties from nucleotide sugars to lipids or chitin polymers. LÄS MER

  5. 5. Characterization of specific domains of the cellulose and chitin synthases from pathogenic oomycetes

    Författare :Christian Brown; Vincent Bulone; Carol Munro; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cellulose biosynthesis; chitin biosynthesis; cellulose synthase genes; chitin synthase genes; oomycetes; Saprolegnia monoica; Microtubule Interacting and Trafficking MIT domain; Pleckstrin Homology PH domain; Biotechnology; Bioteknologi;

    Sammanfattning : Some oomycetes species are severe pathogens of fish or crops. As such, they are responsible for important losses in the aquaculture industry as well as in agriculture. Saprolegnia parasitica is a major concern in aquaculture as there is currently no method available for controlling the diseases caused by this microorganism. LÄS MER