Sökning: "chiral pool"

Hittade 5 avhandlingar innehållade orden chiral pool.

  1. 1. Chiral Pyridine-Containing Ligands for Asymmetric Catalysis. Synthesis and Applications

    Författare :Fredrik Rahm; KTH; []
    Nyckelord :asymmetric catalysis; chiral ligand; chiral pool; oxazoline; crown ether; ditopic receptor; bipyridine; pyridyl alcohol; modular approach; P; N-ligand; diethylzinc; allylic alkylation;

    Sammanfattning : This thesis deals with the design and syntheses of chiral,enantiopure pyridinecontaining ligands and their applicationsin asymmetric catalyis.Chiral pyridyl pyrrolidine ligands and pyridyl oxazolineligands were synthesized and employed in thepalladium-catalysed allylic alkylation of 1,3-diphenyl-2-propenyl acetate with dimethyl malonate. LÄS MER

  3. 2. Natural products from nonracemie building blocks : synthesis of pine sawfly pheromones

    Författare :Michael Larsson; Torbjörn Norin; Gunnar Westman; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Total synthesis; diastereoselective addition; dimethylzinc; Lewis acid; alkyllithium; Organisk kemi; Organic chemistry; Organisk kemi;

    Sammanfattning : This thesis describes a number of synthetic approaches for obtaining chiral, enantiomerically pure natural products, in particular some semiochemicals. This has been accomplished by using various strategies; by starting from compounds from the chiral pool, by using chiral auxiliaries, via enzymatic resolutions or by chemical asymmetric synthesis. LÄS MER

  4. 3. Transition Metal Catalysis for Selective Synthesis and Sustainable Chemistry

    Författare :J. Johan Verendel; Pher G. Andersson; Reko Leino; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Catalysis; Transition metals; Asymmetric catalysis; Hydrogenation; Sustainable chemistry; Kemi med inriktning mot organisk kemi; Chemistry with specialization in Organic Chemistry;

    Sammanfattning : This thesis discusses the preparation and use of transition-metal catalysts for selective organic chemical reactions. Specifically, two different matters have been studied; the asymmetric hydrogenation of carbon-carbon double bonds using N,P-ligated iridium catalysts and the metal-catalyzed transfer of small molecules from biomass to synthetic intermediates. LÄS MER

  5. 4. Chemo- and Enantioselective Hydrogenations : The Struggle of Expanding the Substrate Scope of Iridium Catalyzed Asymmetric Hydrogenations of Olefins

    Författare :Mattias Engman; Pher G. Andersson; Lise-Lotte Gundersen; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi; Organisk kemi; Organic Chemistry;

    Sammanfattning : The asymmetric hydrogenation of olefins is a facile and popular method of reaching chiral products. Whereas ruthenium- and rhodium-catalyzed asymmetric hydrogenations have a long history, the use of iridium in this area is new but fast-growing. LÄS MER

  7. 5. Asymmetric catalysis : ligand design and microwave acceleration

    Författare :Ulf Bremberg; KTH; []
    Nyckelord :;

    Sammanfattning : This thesis deals partly with the design and synthesis ofligands for use in asymmetric catalysis, and partly with theapplication of microwave heating on metal-based asymmetriccatalytic reactions.Enantiomerically pure pyridyl alcohols and bipyridylalcohols were synthesized from the chiral pool for future usein asymmetric catalysis. LÄS MER