Sökning: "chiral chromatography"

Visar resultat 6 - 10 av 45 avhandlingar innehållade orden chiral chromatography.

  1. 6. Molecular Recognition Studies Based on Imprinting Technology

    Författare :Cong Yu; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; imprinting; molecular recognition; polymer; chiral separation; acrylamide; chromatography; functional monomer; cross-linking; hydrogen bonding; hydrophobic interactions; aqueous media; solvent; antibody; mimics; receptor; artificial enzyme; Bioteknik; Biotechnology; Biokemi; Metabolism; Biochemistry;

    Sammanfattning : In this thesis, I have focused on five main research areas: 1). A new type of imprinted polymer has been developed, namely the amide MIP. The amide functional monomers showed better hydrogen bonding capabilities in polar organic solvents and the resulting polymers exhibited good enantiomeric recognition properties in organic media. LÄS MER

  3. 7. Artificial receptors: New opportunities for the exploitation of molecularly imprinted polymers

    Författare :Lei Ye; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Radioimmunoassay; Microsphere; Molecular imprinting; Drug determination; Cross-linking polymerisation; Combinatorial library; Chromatography; Chiral separation; Affinity adsorbent; Biosensor; Receptor; Biochemistry; Metabolism; Biokemi; metabolism; Biotechnology; Bioteknik;

    Sammanfattning : Molecular imprinting, method for creating artificial receptors that are mimics of biological antibodies and receptors, is based on the concept of creating substrate-specific recognition sites in polymeric matrices by means of template polymerisation. The polymeric receptors produced display favourable binding characteristics, such as high affinity and specificity towards the substrate molecules. LÄS MER

  4. 8. Proteins as chiral selectors in liquid chromatography

    Författare :Ingrid Marle; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHARMACY; FARMACI;

    Sammanfattning : .... LÄS MER

  5. 9. Analysis of PCBs with special emphasis on comprehensive two-dimensional gas chromatography of atropisomers

    Författare :Mikael Harju; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Environmental chemistry; PCB; Atropisomers; Chiral; GC×GC; Enantiomeric barriers; Seal; polar; shape selective; Cyclodextrin; 2D; ECD; FID; TOF-MS; Comprehensive two-dimensional GC; Miljökemi; Environmental chemistry; Miljökemi; analytisk kemi; Analytical Chemistry;

    Sammanfattning : There are 209 PCB congeners, 136 of which have been found in technical PCB mixtures and hence may be found in the environment as a result of either intentional or unintentional release. The identification and quantification of the congeners are difficult due to analytical bias from coeluting PCBs and other persistent organic pollutants. LÄS MER

  7. 10. Chiral recognition on cellulases : The active sites of the enzymes are involved

    Författare :Hongbin Henriksson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Biokemi; Biochemistry; Biokemi; biokemi; Biochemistry;

    Sammanfattning : Two cellobiohydrolases (CBH I and CBH II) and endoglucanase I (EG I) fromTrichoderma reesei, and CBH 58 from Phanerochaete chrysosporium were immobilized onsilica as chiral stationary phases (CSPs) in HPLC for enantioseparation of a group ofpharmaceutical compounds. CBH I and CBH 58 wore excellent chiral selectors for β-adrenergic blocking agents, whereas CBH II displayed good enantioselectivity for someother compounds The CBHs share the common feature that their active sites are located intunnels. LÄS MER