Sökning: "chiral auxiliary organolithiums Diels-Alder reaction alkyl radicals triethylborane"

Hittade 1 avhandling innehållade orden chiral auxiliary organolithiums Diels-Alder reaction alkyl radicals triethylborane.

1. 1. Lewis acid Mediated Aza-Diels-Alder Reactions and Asymmetric Alkylations of 2H-azirines

   Författare :Erik Risberg; KTH; []
   Nyckelord :Enantioselective; diastereoselective; vinyl azide; 2H-azirines; aziridines; Lewis acid; chiral ligand; chiral auxiliary organolithiums Diels-Alder reaction alkyl radicals triethylborane.;

   Sammanfattning : This thesis describes the use of 2H-azirines, three-membered unsaturatednitrogen-containing heterocycles, as reactive intermediates ina number of Lewis acid promoted alkylations and Diels-Alderreactions providing synthetically useful aziridines. In order to carry out this investigation a new generalprocedure for the ring closure of vinyl azides, forming theresultant 3-substituted-2H-azirines, was developed applying low boiling solventsin closed reaction vessels at elevated temperatures. LÄS MER