Sökning: "chemotactic gradient"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden chemotactic gradient.

  1. 1. A close-up on neutrophils : Visualizing the mechanisms of their in vivo recruitment and function

    Författare :Sara Massena; Mia Phillipson; Randall S. Jonhson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiogenesis; chemokine; chemotactic gradient; citrullination; hypoxia; inflammation; intraluminal crawling; intravital imaging; PAD enzymes; permeability; proangiogenic; proinflammatory;

    Sammanfattning : A successful immune response depends on prompt and sufficient recruitment of leukocytes from the circulation to infected or injured sites. Mobilization of leukocytes to hypoxic tissues is vital for angiogenesis, i.e. the formation of new blood vessels from preexisting vasculature, and thus crucial for tissue growth and regeneration. LÄS MER

  2. 2. Neutrophil chemotaxis. Analyses of neutrophil chemotaxis i a new fluid gradient chamber

    Författare :Reza Ebrahimzadeh Pirshahid; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell movement; Chemotaxis; Leukocyte; Neutrophil; Human; Filter; Methods; N-Formylmethionine-Leucyl-Phenylalanine; Normal distribution; Partial differential equation;

    Sammanfattning : The leukocytes have, as part of their function in immune system, the ability to leave the bloodstream, penetrate the vascular wall and migrate towards extravascular targets. This behaviour of the leukocytes has been extensively studied both in vivo and in vitro since the 19th century but the mechanisms underlying leukocyte migration are not yet fully understood. LÄS MER

  3. 3. Models for chemotactic migration of a single neutrophil in spatio-temporal gradients of f-MLP : evidence of a temporal mechanism for gradient detection

    Författare :Jonas Tekle; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  4. 4. Motility of human polymorphonuclear leukocytes : An image processing approach

    Författare :Mikael Gustafsson; Erik Gylfe; Linköpings universitet; []
    Nyckelord :Human polymorphonuclear leukocytes; locomotion; phagocytosis; Saccharomyces cerevisiae; membrane transport; intracellular free calcium; cellular pH; water influx; actin dynamics; digital video microscopy; image processing; fura-2; BCECF; DII; MEDICINE; MEDICIN;

    Sammanfattning : Cell motility is essential for polymorphonuclear leukocyte (PMN) function in the defense against invading microorganisms and in inflammatory processes. Using digital video microscopy and image processing, individual cells were studied during random locomotion, chemotactic locomotion and phagocytosis. LÄS MER

  5. 5. Regulation of human eosinophil transmigration across lung epithelium

    Författare :Lixin Liu; Uppsala universitet; []
    Nyckelord :Medical sciences; Eosinophils; regulation; migration; epithelial cells; lung; calcium; CD11b CD18; neutrophils; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Clinical Chemistry; klinisk kemi;

    Sammanfattning : Eosinophil infiltration into the lung tissues and airways is a hallmark of allergic asthma. To reach the lung lumen, eosinophils migrate across the vascular endothelium, through the interstitial matrix and across lung epithelium. LÄS MER