Sökning: "chemoselective"
Visar resultat 1 - 5 av 19 avhandlingar innehållade ordet chemoselective.
1. Development and Applications of Molybdenum-Catalyzed Chemoselective Amide Reduction
Sammanfattning : This thesis covers the development of catalytic methodologies for the mild and chemoselective hydrosilylation of amides. The first part describes the investigation of the Mo(CO)6-catalyzed reduction of carboxamides. LÄS MER
2. Development of advanced chemical biology tools for microbiome metabolism : Chemoselective probes for enhanced metabolomics analysis
Sammanfattning : The human microbiome has a profound impact on host physiology by generating highly reactive compounds that can contribute to the development of diseases. These microbial metabolites have a substantial potential that can serve as valuable indicators or biomarkers for different health conditions. LÄS MER
3. Oxidative Trifluoromethylation and other Functionalization Reactions of Alkenes and Alkynes
Sammanfattning : This thesis concerns the use of various potent oxidants in organic synthesis. The main focus is directed at selectively introducing trifluoromethyl groups into compounds containing double or triple bonds. All reactions proceed under mild conditions and can in most cases be performed on the bench-top. LÄS MER
4. Lipase chemoselectivity - kinetics and applications
Sammanfattning : A chemoselective catalyst is preferred in a chemical reaction where protecting groups otherwise are needed. The two lipases Candida antarctica lipase B and Rhizomucor miehei lipase showed large chemoselectivity ratios, defined as (kcat/KM)OH / (kcat/KM)SH, in a transacylation reaction with ethyl octanoate as acyl donor and hexanol or hexanethiol as acyl acceptor (paper I). LÄS MER
5. Photochemical Ligation Techniques for Carbohydrate Biosensors and Protein Interaction Studies
Sammanfattning : This thesis concerns the development of surface ligation techniques for the preparation of carbohydrate biosensors. Several methodologies were developed based on efficient photochemical insertion reactions which quickly functionalize polymeric materials, with either carbohydrates or functional groups such as alkynes or alkenes. LÄS MER