Sökning: "chemoprevention"

Visar resultat 1 - 5 av 8 avhandlingar innehållade ordet chemoprevention.

  1. 1. Drug repositioning in chemoprevention of colorectal cancer

    Författare :Naiqi Zhang; Allmänmedicin och klinisk epidemiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Drug repositioning; Colorectal cancer CRC ; Pharmacoepidemiology; Chemoprevention; Melatonin; Proguanil; Atovaquone; Selective serotonin reuptake inhibitor SSRI ;

    Sammanfattning : BackgroundColorectal cancer (CRC) ranks as the third most frequently occurring cancer and the second leading cause of cancer-related deaths worldwide. In response to the high demand for an effective prevention strategy, chemoprevention, using medications to block the pathogenetic pathways of disease, might be an attractive strategy to offer a more effective option at a low cost. LÄS MER

  3. 2. The effects of flaxseed and tamoxifen on the inflammatory microenvironment in normal breast tissue and in breast cancer

    Författare :Gabriel Lindahl; Charlotta Dabrosin; Signe Borquist; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast cancer; inflammation; chemoprevention; tamoxifen; phytoestrogens; flaxseed; enterolactone; interleukins; osteopontin; chemokines; matrix metalloproteases; microdialysis;

    Sammanfattning : Breast cancer is the most common cancer among women worldwide today. Nearly 9000 women are diagnosed with breast cancer in Sweden yearly and despite advantages in diagnostics and treatments approximately 1400 women still die from their disease every year. LÄS MER

  4. 3. A study of two major challenges in prostate cancer : effective chemo-prevention and overcoming resistance to hormonal and chemotherapy

    Författare :Yuanjun Ma; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : For men, over the course of a lifetime the risk of developing prostate cancer is 1 in 9. Both the illness itself and treatment affect quality of life in multiple aspects, including urinary problems, pain, and sexual dysfunction. LÄS MER

  5. 4. Characterization of the mechanisms of action of anticancer agents in vitro and monitoring their effects in vivo

    Författare :Hamdiye Erdal; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chemotherapeutic drug resistance is a major clinical problem and cause for failure in the therapy of human cancer. Mutations in apoptotic programs may promote tumour progression and reduce the efficacy of cancer therapy. LÄS MER

  7. 5. Prostanoids and colorectal cancer

    Författare :Annika Gustafsson Asting; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer prostanoid receptors cyclooxygenase PGE2 transcription factors;

    Sammanfattning : Tumor disease is a main cause of death in Western countries and a most common malignancy is colorectal cancer (CRC). Growing tumors are dependent on interactions among several different cells as well as signaling pathways. LÄS MER