Sökning: "chemokine"
Visar resultat 21 - 25 av 279 avhandlingar innehållade ordet chemokine.
21. EFFECTOR T CELL HOMING TO THE SMALL INTESTINAL MUCOSA
Sammanfattning : The intestinal mucosa, including the intestinal epithelium and underlying lamina propria (LP), contains a large number of effector/memory T cells that are thought to play a central role in the generation and maintenance of mucosal immune responses and in maintaining mucosal integrity. The work in this thesis investigates the mechanisms regulating effector T cell recruitment to the small intestinal mucosa focusing on the role of chemokine receptors in this process. LÄS MER
22. Lyme Neuroborreliosis - Diagnosis and Treatment
Sammanfattning : Lyme neuroborreliosis, the infection of the nervous system by the tick-borne bacterium Borrelia burgdorferi, is a common infection in the temperate parts of the Northern hemisphere. Manifestations of the disease include facial palsy, radicular pain, sensory disturbances, and occasionally CNS symptoms such as confusion and paraparesis. LÄS MER
23. Role of Neutrophils and Innate Immune Mechanisms in Urinary Tract Infections
Sammanfattning : Urinary tract infections (UTI) are among the most common infections in man. Despite their prevalence, information on the molecular mechanisms defects that explain the increased susceptibility to disease are lacking. LÄS MER
24. Low CXCR1 Expression and Susceptibility to Acute Pyelonephritis
Sammanfattning : Urinary tract infections (UTIs) are clustered in certain individuals but the molecular basis of disease susceptibility is not known. A single gene was shown to control the susceptibility to acute pyelonephritis and renal scarring in mice. LÄS MER
25. On the role of mast cells in chemokine-induced leukocyte recruitment
Sammanfattning : Leukocyte recruitment is considered to playa key role in numerous inflammatory diseases. Tissue accumulation of Jeukocytes is a multi-steps process comprising rolling, adhesion and transmigration. LÄS MER