Sökning: "chemokine receptor"

Visar resultat 21 - 25 av 139 avhandlingar innehållade orden chemokine receptor.

  1. 21. HIV-1 infection and loss of serological memory : the role of altered expression of B-cell chemokine receptors, timing of HAART and impaired antibody affinity maturation

    Författare :Alberto Cagigi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Currently, big efforts in HIV-1 research are devoted to the design of a HIV-1 vaccine. However, no successful vaccine is yet available, also due to the lack of basic knowledge in HIV-1 pathogenesis which is still profound. LÄS MER

  3. 22. Immune dysregulation in HIV-1 infected lymphoid tissue

    Författare :Homira Behbahani; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV-1; HAART; cytokines; chemokines; lymphoid tissue; perforin; Nef; LIF; placenta; chemokine receptor;

    Sammanfattning : Lymphoid compartments are major sites for HIV-1 replication. We evaluated cytokines, chemokines and immunological effector function at the single cell level in lymphoid tissues in chronically HIV-1 infected patients. LÄS MER

  4. 23. HIV-1 phenotype and genetic variation in vertical transmission

    Författare :Peter Clevestig; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV; co-receptor use; diversity; clade; sequon.;

    Sammanfattning : HIV-1 vertical transmission is increasing worldwide despite that successful strategies are available. Reduction of vertical transmission has been established by antiretroviral prophylaxis and elective Caesarian section, but this has been limited to the developed countries. LÄS MER

  5. 24. HIV-1 infection during pregnancy and in children : significance of HIV-1 variability and the placental barrier

    Författare :Charlotte Casper; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :biological phenotype; genetic subtype; chemokine receptor; coreceptor; mother- to-child transmission; placenta; disease progression; child; pregnancy;

    Sammanfattning : With the global increase in human immunodeficiency virus 1 (HIV-1) infection in women of childbearing age, there has also been an alarming increase in the number of mother-to-child transmissions of HIV-1. Although antiretroviral therapy and Cesarian section have been demonstrated to significantly decrease the vertical transmission rate of, these interventions are not widely available in the developing world. LÄS MER

  7. 25. T lymphocyte and NK cell function in pulmonary inflammation in sarcoidosis

    Författare :Kianoosh Katchar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :T lymphocytes; cytokines; activation markers; chemokine receptors; T regulatory cells; sarcoidosis.;

    Sammanfattning : The focus of this thesis is on the role of T lymphocytes and Natural Killer cells in sarcoidosis, which is an inflammatory interstitial pulmonary disorder of unknown etiology. An accumulation of CD4+ T helper cells in the lungs is a characteristic feature of this disease. LÄS MER