Sökning: "chemical genomics"

Visar resultat 1 - 5 av 19 avhandlingar innehållade orden chemical genomics.

  1. 1. Development of chemical biology tools for metabolomics analysis : Phase II modifications as a link between host and microbiota co-metabolism

    Författare :Mario S. P. Correia; Daniel Globisch; Warwick Dunn; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Metabolomics; Chemical biology; sulfatase; Glucuronides; Phase II modifications; Microbiome; co-metabolism; method development; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry;

    Sammanfattning : Biomarker discovery is an extremely important field for early disease detection. New selective molecular markers are in high demand, as an earlier disease detection can lead to improved patient care. LÄS MER

  3. 2. Latent variable based computational methods for applications in life sciences : Analysis and integration of omics data sets

    Författare :Max Bylesjö; Johan Trygg; Tormod Naes; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemometrics; orthogonal projections to latent structures; OPLS; O2PLS; K-OPLS; kernel-based; non-linear; regression; classification; Populus; Chemistry; Kemi;

    Sammanfattning : With the increasing availability of high-throughput systems for parallel monitoring of multiple variables, e.g. levels of large numbers of transcripts in functional genomics experiments, massive amounts of data are being collected even from single experiments. LÄS MER

  4. 3. Cell wall chemotyping for functional genomics : applications of pyrolysis-gas chromatography / mass spectrometry

    Författare :Lorenz Gerber; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The interest in lignocellulose as a sustainable resource for energy and materials has fueled research on biotechnology applications in tree breeding to improve biomass production and wood properties. An important aspect of this research is the basic understanding of gene function in wood formation, where analysis of wood chemistry and wood structure is of utmost importance. LÄS MER

  5. 4. Genomics and metabolomics in the North Atlantic deep-sea sponge Geodia barretti

    Författare :Karin Steffen; Paco Cárdenas; Ulf Göransson; Anders Backlund; Susanna López-Legentil; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; demosponge; whole genome sequencing; population genetics; peptide synthesis; Farmakognosi; Pharmacognosy;

    Sammanfattning : Sponges are among the earliest diverging taxa in the animal tree of life. They are sessile, filter-feeding animals found in marine and freshwater habitats. Many species are characterized by a close, specific and consistent association with microbes, mainly Bacteria and Archaea. LÄS MER

  7. 5. Genetic Aspects of Environmental Disturbances in Marine Ecosystems : Studies of the Blue Mussel in the Baltic Sea

    Författare :Josefine Larsson; Mats Grahn; Inger Porsch-Hällström; Katarzyna Smolarz; Andrew Whitehead; Södertörns högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Blue mussel; Baltic Sea; anthropogenic disturbance; pollution; sewage effluents; harbors; genetics; genomics; Environmental Studies; Miljövetenskapliga studier; Östersjö- och Östeuropaforskning; Baltic and East European studies;

    Sammanfattning : Anthropogenic environmental changes can serve as drivers for evolutionary responses in wild populations. To predict the long-term impact of anthropogenic changes on populations, it is crucial to understand the genetic effects caused by these disturbances. LÄS MER