Sökning: "chemical diversity"

Visar resultat 1 - 5 av 143 avhandlingar innehållade orden chemical diversity.

  1. 1. Exploring evolutionary and chemical space using chemoinformatic tools and traditional methods in pharmacognosy

    Författare :Astrid Henz Ryen; Anders Backlund; Thierry Kogej; Fernando B. Da Costa; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; angiosperm chemistry; physicochemical properties of plant specialized metabolites; chemical diversity; chemical space; sesquiterpene lactones; scaffold diversity; molecular framework; cluster analysis; ECFP6; Lindera benzoin; sesquiterpenes; anti-inflammatory; Farmakognosi; Pharmacognosy;

    Sammanfattning : The number of new drugs coming to the market is declining while interest in lead discovery from natural resources is seeing a revival. Although methods for isolation and identification of natural products have advanced tremendously, methods for selection of potential leads have fallen behind. LÄS MER

  3. 2. Development of advanced chemical biology tools for microbiome metabolism : Chemoselective probes for enhanced metabolomics analysis

    Författare :Weifeng Lin; Daniel Globisch; Frank Schroeder; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chemical biology; Chemoselective modification; Chemical metabolomics; Bioorganic; Microbiome metabolism; Kemi; Chemistry;

    Sammanfattning : The human microbiome has a profound impact on host physiology by generating highly reactive compounds that can contribute to the development of diseases. These microbial metabolites have a substantial potential that can serve as valuable indicators or biomarkers for different health conditions. LÄS MER

  4. 3. Implications of feedstock diversity on forest-based ethanol production

    Författare :Balazs Franko; Avdelningen för kemiteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Ethanol; Lignocellulose; Softwood; Spruce; Bark; Forest residues; Steam pretreatment; Enzymatic hydrolysis;

    Sammanfattning : The utilization of lignocellulosic biomass to produce biofuels, such as bioethanol, has the potential to provide a sustainable alternative to fossil fuels, and thus mitigate greenhouse gas emissions from the transportation sector.Forest biomass is expected to be a significant source of such biomass, as it can serve as an abundant and sustainable feedstock for bioethanol production. LÄS MER

  5. 4. Cyclotides evolve : Studies on their natural distribution, structural diversity, and activity

    Författare :Sungkyu Park; Göransson Ulf; Lars Bohlin; Mohamed Marahiel; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; cyclotide; cyclic cystine knot; evolution; peptide synthesis; chemical ligation; QSAR; Viola; Violaceae; phylogeny; Farmakognosi; Pharmacognosy;

    Sammanfattning : The cyclotides are a family of naturally occurring peptides characterized by cyclic cystine knot (CCK) structural motif, which comprises a cyclic head-to-tail backbone featuring six conserved cysteine residues that form three disulfide bonds. This unique structural motif makes cyclotides exceptionally resistant to chemical, thermal and enzymatic degradation. LÄS MER

  7. 5. Chemical Pathways for Galactoglucomannan-based Materials

    Författare :Jens Voepel; Ann-Christine Albertsson; Ulrica Edlund; Søren Hvilsted; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Polysaccharides; hemicelluloses; galactoglucomannan; renewable; chemical modification; hydrogels; swelling; crosslinking; release; SET-LRP; living polymerization; grafting; hybrid materials; Polymer chemistry; Polymerkemi;

    Sammanfattning : Polysaccharides are an important resource for a variety of products, from food via fuel supply to functional materials of every kind. Due to their natural diversity they can be found in many special applications, e.g. in the biomedical sector and are the major renewable resource for materials of many kinds. LÄS MER