Sökning: "changes in biological markers"

Visar resultat 1 - 5 av 106 avhandlingar innehållade orden changes in biological markers.

1. 1. Chicken domestication : Effects of tameness on brain gene expression and DNA methylation

   Författare :Johan Bélteky; Per Jensen; Anna Kukekova; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : Domestication greatly increases phenotypic variation in a short time span, with selection for a single phenotype and a plethora of associated phenotypic changes as an outcome of the process. The domestication process influences the underlying genomic architecture of a species, and the success and speed of the process is likely influenced by it. LÄS MER

3. 2. Neurodevelopmental Consequences of Exposure to Paracetamol (Acetaminophen) and Related Drugs : Experimental studies in mice

   Författare :Gaëtan Philippot; Robert Fredriksson; Vesna Jevtovic-Todorovic; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; paracetamol acetaminophen ; developmental neurotoxicology; delta9-tetrahydrocannabinol THC ; ibuprofen; endocannabinoid system; neonatal mice; brain growth spurt; behavior; Biology with specialization in Environmental Toxicology; Biologi med inriktning mot miljötoxikologi;

   Sammanfattning : Paracetamol (acetaminophen) is the analgesic pharmaceutical most commonly used during pregnancy and early life. While therapeutic doses of paracetamol are considered harmless during these periods, recent findings in both humans and rodents suggest a link between developmental exposure to paracetamol and behavioral consequences later in life. LÄS MER

4. 3. Climate change time machine : Adaptation to 30 years of warming in the Baltic Sea

   Författare :Friederike Ermold; Anssi Laurila; Jukka Jokela; Kerstin Johannesson; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; climate change; thermal adaptation; evolution; Baltic Sea; Biotest Basin; ecological interactions; biological invasions; phenotypic plasticity; Biologi med inriktning mot populationsbiologi; Biology with specialization in Population Biology;

   Sammanfattning : Earth mean surface temperature has increased by 1 °C since the industrial revolution, and this has already had considerable effects on animal and plant species. Ecological responses to the warming climate – often facilitated via phenotypic plasticity – are ubiquitous. LÄS MER

5. 4. Developmental Neurotoxicity of Environmental Pollutants : Effects on neuronal protein markers after neonatal exposure

   Författare :Iwa Lee; Henrik Viberg; Elena Jazin; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental neurotoxicity; Neonatal exposure; Protein markers; Environmental pollutants; Biologi med inriktning mot ekotoxikologi; Biology with specialization in Environmental Toxicology;

   Sammanfattning : This thesis focused on investigations of the developmental neurotoxic effects of bisphenol A (BPA) or perfluorohexane sulfonate (PFHxS), after a single neonatal exposure, during a critical period of the brain development in mice.BPA is a well-known industrial chemical used in the production of polymer products and PFHxS is used as an industrial additive as a surfactant. LÄS MER

7. 5. T Cells and NK Cells in Coronary Artery Disease : Longitudinal and methodological studies in humans

   Författare :Karin Backteman; Jan Ernerudh; Lena Jonasson; Joachim Lundahl; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : Coronary artery disease (CAD) is the leading cause of death worldwide and most often due to atherosclerosis. Atherosclerosis is a chronic inflammatory process that involves the arteries, inclouding those that supply blood to the heart muscle. LÄS MER