Sökning: "cervical ripening."

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden cervical ripening..

1. 1. Clinical, biochemical and morphological aspects of cervical ripening in the first trimester

   Författare :Nina Vukas Radulovic; Göteborgs universitet; []
   Nyckelord :cervical ripening; misoprostol; nitric oxide; electron microscopy; miscarriage; IL-8; MMP-1; MMP-8; MMP-9;

   Sammanfattning : Background: The uterine cervix has the ability to be transformed from being a rigid organ in non-pregnant women to become a loose structure that dilates and allows passage of the foetus at parturition. This process, cervical ripening, has been described similar to an inflammatory reaction of the extracellular matrix involving activation of inflammatory cytokines, matrix metalloproteinases and breakdown of the collagen framework. LÄS MER

3. 2. Endocrine and neuronal interactions in human cervical ripening

   Författare :Ylva Stjernholm; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Estrogen receptor; progesterone receptor; IGF-I mRNA; thioredoxin; PGP 9.5. neuropeptides; dendritic cells;

   Sammanfattning : Objective: To evaluate the hormonal and neuronal environment in human cervix during pregnancy and parturition. Methods: Cervical biopsy specimens were obtained transvaginally, and serum samples were drawn simultaneously. LÄS MER

4. 3. Cervical ripening : an inflammatory process involving cytokines, metalloproteinases and foetal fibronectin

   Författare :Maria Sennström; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :cervical ripening; interleukin-8; interleukin-6; granulocyte colony stimulating factor; metalloproteinase- 1; -3 - and -8; foetal fibronectin;

   Sammanfattning : The aim of the thesis was to identify cytokines, metalloproteinases and foetal fibronectin in human cervical tissue and to investigate if changes are of importance for the final cervical ripening. The human cervical ripening is a prerequisite for a normal start and progress of labour. LÄS MER

5. 4. Mediators of cervical ripening in preterm birth : experimental and clinical investigations

   Författare :Susanne Abelin Törnblom; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Cervix; preterm; cervical ripening; cytokines; chemokines; cyclooxygenase COX ; prostaglandin dehydrogenase PGDH ; induction; labour; nitric oxide; PgE2-gel; pregnancy; preterm labour;

   Sammanfattning : Background: Preterm birth (PTB) is by far the leading worldwide cause of infant mortality and morbidity. Despite decades of research, the frequency of PTB has not decreased and the basic mechanisms initiating the onset of labour are still poorly understood. Vaginal preterm birth cannot take place without cervical softening and remodelling. LÄS MER

7. 5. Nitric oxide donors in labor management

   Författare :Maria Bullarbo; Göteborgs universitet; []
   Nyckelord :cervical ripening; labor induction; nitric oxide donor; retained placenta;

   Sammanfattning : ABSTRACT Nitric oxide donors in labor management Maria Bullarbo Department of Obstetrics and Gynecology Institute of Clinical Sciences Background: Nitric oxide (NO), a free radical with ultra-short half-life synthesized from L- arginine by the enzyme nitric oxide synthase (NOS), is in the human involved in many physiological and pathophysiological processes, including different reproductive processes. During pregnancy NO is produced endogenously in the human uterine cervix and placenta. LÄS MER