Sökning: "cervical intraepithelial neoplasia CIN"

Visar resultat 1 - 5 av 25 avhandlingar innehållade orden cervical intraepithelial neoplasia CIN.

  1. 1. Targeting the human papillomavirus for prevention of cervical cancer

    Författare :Pontus Naucler; Malmö Klinisk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bakteriologi; virologi; Mikrobiologi; mycology; virology; bacteriology; prevention; Microbiology; CIN; vaccine; cervical intraepithelial neoplasia; screening; cervical cancer; Human Papillomavirus; HPV; mykologi; Public health; epidemiology; Folkhälsa; epidemiologi;

    Sammanfattning : Different types of human papillomavirus (HPV) vary in the extent they cause precursor lesions (CIN) and cancer. There are limited long-term efficacy data on HPV testing in primary screening Among 72 cervical cancers in Mozambique, HPV 16 and 18 were the most frequent HPV types (69% of cases). LÄS MER

  3. 2. Molecular mechanisms in cervical carcinogenesis : Studies of clonality, somatic genetic alterations and human papillomavirus variants in cervical pre-invasive and invasive cancer

    Författare :Zhongmin Guo; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; cervical cancer; CIN; clonality; X-chromosome inactivation; LOH; HPV; chromosome 3p; chromosome 6; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Sammanfattning : Cervical cancer derives from a series of pre-invasive cervical neoplastic lesions termed CIN I-III (Cervical Intraepithelial Neoplasia) via typical multiple-step processes. In contrast to premalignant disorders in other organs, different degrees of CIN possess a distinct biological behaviour where a proportion spontaneously regress or persist, whereas some progress to invasive cancer. LÄS MER

  4. 3. Molecular Pathogenesis of Cervical Carcinoma : Analysis of Clonality, HPV16 Sequence Variations and Loss of Heterozygosity

    Författare :Xinrong Hu; Björn Hagmar; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; cervical carcinoma; CIN; HPV; LOH; X-chromosome inactivation; clonality; molecular pathogenesis; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Sammanfattning : A previous model of morphological pathogenesis assumed that cervical carcinoma is of monoclonal origin and progresses through multiple steps from normal epithelium via CINS into invasive carcinomas. The aim of this study was to investigate the molecular mechanism of pathogenesis of cervical neoplasia. LÄS MER

  5. 4. Minimal conization with carbon dioxide laser for treatment of cervical intra-epithelial neoplasia

    Författare :Zoltan Bekassy; Lund Obstetrik och gynekologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gynaecology; Obstetrics; preterm birth; pregnancy; laser; follow-up; conization; Cervical carcinoma; cervical intraepithelial neoplasia; andrology; reproduction; sexuality; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet;

    Sammanfattning : 3,100 non-pregnant women and 85 pregnants were miniconized during the 15-year period ending 1994 . The outpatient procedure of minimal conization using a freehand-guided, high power 60W carbon dioxide laser focused to 0.1 mm in spot-size, giving high power density 165,000 W/cm2, produces single-piece tissue specimens for histological examination. LÄS MER

  7. 5. Cervical cancer prevention Studies on possible improvements

    Författare :Björn Strander; Göteborgs universitet; []
    Nyckelord :Cervical intraepithelial neoplasia; cytology; colposcopy; HPV; cervical neoplasm; epidemiology; treatment; follow up;

    Sammanfattning : Aims: The aim of this study is to target and assess possible improvements for women attending cervical cancer screening programs. Methods: In a randomized study the use of ThinPrep liquid based cytology (LBC) was tested against conventional cytology. LÄS MER