Sökning: "cerebral small vessel disease"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden cerebral small vessel disease.

  1. 1. Magnetic resonance imaging markers of cerebral small vessel disease in an elderly population – association with cardiovascular disease and cognitive function

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Ruta Nylander; Uppsala universitet.; [2017]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Magnetic resonance imaging; cerebral perfusion; small vessel disease; cognitive function; Radiology; Radiologi;

    Sammanfattning : Cerebral small vessel disease (SVD) is identifiable by clinical, neuroimaging, neuropathological and cognitive findings.The aim of this thesis was to assess SVD and cerebral perfusion on magnetic resonance imaging (MRI) in a 75-year-old population and compare the findings with scars of myocardial infarctions, cardiovascular risk markers and cognitive function. LÄS MER

  2. 2. Risk factors for development of neurocognitive disorders

    Detta är en avhandling från Lund University, Faculty of Medicine

    Författare :Anna-Märta Gustavsson; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2019]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vascular risk factors; dementia; Alzheimer’s disease; ß-amyloid; white matter hyperintensities; cerebral small vessel disease;

    Sammanfattning : AbstractVascular risk factors are believed to be involved in dementia development by increasing risk of the most common dementia types, Alzheimer’s disease (AD) and vascular dementia. The aim of this thesis was to study if risk factorsaffect key brain pathology directly, by using biomarkers for dementia in preclinical stages, and to assess previous findings in a large population-based setting. LÄS MER

  3. 3. CADASIL : a pure model for studying cerebral small vessel disease

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Neurobiology, Care Sciences and Society

    Författare :Mahmod Panahi; Karolinska Institutet.; Karolinska Institutet.; [2019]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy (CADASIL) is caused by a mutation on the NOTCH3 gene. The pathological driver behind this disease is the loss of vascular smooth muscle cells (VSMCs) in small blood vessels and subsequent fibrotic thickening of the vessel, causing stenosis. LÄS MER

  4. 4. Cerebral microbleeds and cognitive impairment

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Clinical Science, Intervention and Technology

    Författare :Sara Shams; Karolinska Institutet.; Karolinska Institutet.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Background: With increasingly ageing populations comes an increased prevalence of cognitive impairment and dementia. The pathophysiology behind dementia is still unknown, and there is no cure. LÄS MER

  5. 5. Molecular and clinical markers in ischaemic cerebrovascular disease

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Clinical Neuroscience

    Författare :Ioanna Markaki; Karolinska Institutet.; Karolinska Institutet.; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Ischaemic stroke and TIA, together labelled as Ischaemic Cerebrovascular Disease (ICVD), is a heterogeneous, complex disorder with great impact on morbidity and mortality worldwide. Genetic predisposition and environmental factors interact and confer susceptibility to different pathologies that are associated with increased ICVD risk. LÄS MER