Sökning: "cerebral perfusion"

Visar resultat 1 - 5 av 72 avhandlingar innehållade orden cerebral perfusion.

  1. 1. Experimental cardiopulmonary cerebral resuscitation : A study of cerebral perfusion with special reference to the postresuscitation disturbances

    Författare :Ala Nozari; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Cardiac arrest; cardiopulmonary resuscitation; cerebral blood flow; post-resuscitation period; epinephrine; vasopressin; aortic occlusion; isoprostane; Kirurgi; Surgery; Kirurgi; Anestesiologi; Anaesthesiology;

    Sammanfattning : Ischemic neuronal injury continues to be a major delimiting factor in achieving successful clinical outcomesafter resuscitation from cardiac arrest. In this thesis, a pig model of cardiopulmonary resuscitation (CPR) wasused to address the effects of different interventions on cerebral blood flow and oxygenation during CPR and theinitial postresuscitation period. LÄS MER

  3. 2. Cerebral Perfusion and Metabolism during Experimental Extracorporeal Circulation

    Författare :Ove Jonsson; Stefan Thelin; Fredrik Lennmyr; Sven-Erik Ricksten; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cerebral perfusion; Experimental brain research; Experimentell hjärnforskning; Thoraxkirurgi; Thorax Surgery;

    Sammanfattning : Neurologic injuries are major causes of mortality and morbidity after cardiac surgery. This thesis aimed to investigate cerebral metabolism and perfusion abnormalities in pigs during hypothermic circulatory arrest, selective antegrade cerebral perfusion (SACP) and extracorporeal circulation following progressive venous stasis. LÄS MER

  4. 3. Cerebral CT - and MRI perfusion: Techniques and clinical application in iNPH

    Författare :Doerthe Ziegelitz; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cerebral perfusion; idiopathic normal pressure hydrocephalus; computed tomography perfusion; dynamic suceptibility contrast MRI;

    Sammanfattning : Idiopathic normal pressure hydrocephalus (iNPH) is a disorder of the elderly, defined by slowly progressive impairment of gait and balance, cognitive decline, and incontinence. Disturbance of the cerebrospinal fluid (CSF) dynamics results in ventriculomegaly without intracranial pressure increase. LÄS MER

  5. 4. Thoracic Aortic Surgery : Epidemiology, Outcomes, and Prevention of Cerebral Complications

    Författare :Christian Olsson; Stefan Thelin; Jan van der Linden; Uppsala universitet; []
    Nyckelord :Surgery; Aorta; Thoracic; Aortic aneurysms; Aortic disease; Cardiovascular surgical procedures; Epidemiology; Registries; Treatment outcome; Survival analysis; Cerebral infarction; Near-infrared spectroscopy; Quality of life; Perfusion; Kirurgi;

    Sammanfattning : The mortality of thoracic aortic diseases (mainly aneurysms and dissections) is high, even with surgical treatment. Epidemiology and long-term outcomes are incompletely investigated. Stroke is a major complication contributing to mortality, morbidity, and possibly to reduced quality of life. LÄS MER

  7. 5. Optimisation and Validation of Dynamic Susceptibility Contrast MRI Perfusion Measurements

    Författare :Linda Knutsson; Lund Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nukleärmedicin; radiobiologi; Nuclear medicine; radiobiology; radiologi; tomografi; medicinsk instrumentering; tomography; medical instrumentation; Clinical physics; cerebral blood volume; mean transit time; cerebral blood flow; perfusion; dynamic susceptibility contrast MRI arterial input function; Klinisk fysiologi; radiology;

    Sammanfattning : The studies presented in this thesis concern the optimisation and evaluation of the dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) technique for the assessment of perfusion-related parameters of the brain, such as cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT). Several methodological factors influence these measurements, for example, contrast-agent administration, arterial input function (AIF) registration, choice of deconvolution algorithm and the choice of pulse-sequence parameters. LÄS MER