Sökning: "cerebral gliomas"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden cerebral gliomas.

  1. 1. Preoperative MRI and PET in suspected low-grade gliomas : Radiological, neuropathological and clinical intersections

    Författare :Anna Falk Delgado; Elna-Marie Larsson; Anja Smits; Jens Sörensen; John Hald; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Low-grade glioma; MRI; PET; FA; MD; Perfusion; Diffusion; Neuropathology; Oligodendroglioma; Astrocytoma; PET; tractography; DTI; DTT; Radiologi; Radiology;

    Sammanfattning : Background: Gliomas are neuroepithelial tumours classified by cell type and grade. In adults, low-grade gliomas are comprised mainly of astrocytomas and oligodendrogliomas grade II. LÄS MER

  3. 2. Expression of TGF- isoforms, their receptors and related SMAD proteins in brain pathology : Immunohistochemical studies focusing on infarcts, abscesses and malignant gliomas

    Författare :Ahmad Khaled Ata; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; TGF-beta receptor; SMAD; brain; infarct; abscess; glioma; experimental; human; Genetik; Clinical genetics; Klinisk genetik; Genetics; genetik;

    Sammanfattning : This thesis focuses on the immunohistochemical expression of transforming growth factor beta(TGFβ) isoforms, their receptors and TGF-β-related SMAD proteins in brain pathology, chiefly in-farcts. One key question was whether the expressions of these compounds are altered within glial cells, endothelial cells of microvessels and other cell types in the vicinity of infarcts. LÄS MER

  4. 3. Significance of white matter anatomy in interpreting features and behaviour of low-grade gliomas and implications for surgical treatment

    Författare :Francesco Latini; Mats Ryttlefors; Lorenzo Bello; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; White matter; Cerebral gliomas; DTI; Brain-Grid; Brain mapping; Human connectome project; Anatomi; Human Anatomy; Oncology; Onkologi; Neurokirurgi; Neurosurgery; Radiology; Radiologi; Neurology; Neurologi;

    Sammanfattning : Diffuse gliomas are extremely heterogeneous tumours characterized by slow growth but extensive infiltration. Their kinetic features reflect the complex interaction over time with the surrounding brain, influencing treatment planning and outcome. LÄS MER

  5. 4. Regulation of ongoing DNA synthesis in normal and neoplastic brain tissue

    Författare :Juan Sebastián Yakisich; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :DNA replication - Cell cycle - Brain - Gliomas - Tissue mini-unit - Protein kinases - Proteases Inhibitors - Roscovitine;

    Sammanfattning : The treatment of human brain tumour is challenging in part due to the blood brain barrier and in part due to the specific biology of brain tumours that confer resistance to chemotherapy. For instance, the 5 years survival rate for patients carrying intracranial glioblastoma multiforme has remained at 4-5 % for the last 30 years. LÄS MER

  7. 5. Nitric Oxide Regulation during Anti-tumor Immunotherapy

    Författare :Wiaam Badn; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Immunologi; serology; Immunology; Medicin människa och djur ; immunotherapy; Medicine human and vertebrates ; immunosuppression; PGE2; Nitric oxide; serologi;

    Sammanfattning : During tumor progression a strong immunosuppression is developed and is believed to be the major reason why immunotherapy fails. This suppression is induced in response to factors produced from tumor cells, but can also be induced after immunotherapy. LÄS MER