Sökning: "ceramide"

Visar resultat 21 - 25 av 36 avhandlingar innehållade ordet ceramide.

1. 21. The advantages of being small : Glycosyltransferases in many dimensions and glycolipid synthesis in Mycoplasma Pneumoniae

   Författare :Maria Rosén Klement; Åke Wieslander; Christelle Breton; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Glycosyltransferase; lipid; membrane; glycolipid; ACC; PLS-DA; Biochemistry; Biokemi; biokemi; Biochemistry;

   Sammanfattning : The synthesis and breakdown of sugars is one of the most important functions in Nature. Consequently, sugar structures are used both as energy storage and as building blocks to stabilise and protect the cell. The formation of these structures is performed by glycosyltransferases (GT), an enzyme group structurally conserved within all kingdoms. LÄS MER

3. 22. Influence of host genetics on innate immunity and susceptibility to urinary tract infection

   Författare :Bryndis Ragnarsdottir; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophils; IRF3; Innate Immunity; urinary tract infections; acute pyelonephritis; asymptomatic bacteriuria; Toll-like receptor 4; CXCR1; TLR4 adaptors; polymorphisms;

   Sammanfattning : It has been known for a long time that the clinical manifestations of urinary tract infections (UTI) differ markedly between individuals, ranging from a sometimes beneficial, asymptomatic state to life threatening infections. This variability in clinical manifestation can be explained in part by the arsenal of virulence factors of the bacteria but the predisposition of the patient is equally important. LÄS MER

4. 23. Cannabinoids as modulators of cancer cell viability, neuronal differentiation, and embryonal development

   Författare :Sofia Gustafsson; Stig Jacobsson; Birgitta Sander; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cannabinoids; cell viability; neuronal differentiation; colorectal cancer; chick embryo; biokemisk farmakologi; biochemical pharmacology; Toxicology; toxikologi;

   Sammanfattning : Cannabinoids (CBs) are compounds that activate the CB1 and CB2 receptors. CB receptors mediate many different physiological functions, and cannabinoids have been reported to decrease tumor cell viability, proliferation, migration, as well as to modulate metastasis. LÄS MER

5. 24. Responding Model Membranes. Lipid Phase Behaviour, Domain Formation and Permeability

   Författare :Emma Sparr; Fysikalisk kemi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Water and solute flux; Gradients; Monolayer; Two-dimensional crystals; Line activiy; Osmotic stress; Interlamellar forces; Phospholipid-cholesterol interactions; Phase transitions; Bilayer stack; Stratum corneum; Physical chemistry; Fysikalisk kemi;

   Sammanfattning : This thesis concerns the interplay between the lipid phase behaviour, domain formation and the permeability of bilayer membranes. An essential part of this work has been the understanding of the phase transitions and equilibrium properties of lipid bilayers. LÄS MER

7. 25. C. elegans PAQR-2 ‒ A Regulator of Membrane Homeostasis

   Författare :Emma Svensk; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PAQR; LRRIG; glucose; membrane fluidity; desaturase; homeoviscous adaptation;

   Sammanfattning : The progestin and adipoQ receptor (PAQR) protein family is characterized by a 7-transmembrane domain, and a topology reversed that of G-protein coupled receptors, i.e. the N-terminus resides in the cytoplasm. LÄS MER