Sökning: "cephalosporin C"

Hittade 4 avhandlingar innehållade orden cephalosporin C.

  1. 1. Evasion and Attack: Structural Studies of a Bacterial Albumin-binding Protein and of a Cephalosporin Biosynthetic Enzyme

    Författare :Sara Lejon; Janos Hajdu; Karin Valegård; Martin Noble; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; human serum albumin; GA module; albumin-binding; Finegoldia magna; deacetylcephalosporin C acetyltransferase; cephalosporin C; antibiotic; beta-lactam; biosynthesis; Acremonium chrysogenum; X-ray crystallography; Structural biology; Strukturbiologi;

    Sammanfattning : This thesis describes the crystal structures of two proteins in the context of combatting bacterial infections. The GA module is a bacterial albumin-binding domain from a surface protein expressed by pathogenic strains of the human commensal bacterium Finegoldia magna. LÄS MER

  3. 2. Clostridioides difficile infections: Preventive strategies

    Författare :Jon Edman-Wallér; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clostridioides difficile; Transmission; Antibiotic stewardship; Outbreak surveillance; Mathematical modelling; Infection Prevention and Control;

    Sammanfattning : Clostridioides difficile infections primarily affect elderly, hospitalised patients treated with antibiotics and are among the most common healthcare-related infections. This thesis aimed to improve the understanding of the best prevention strategies for this disease, particularly in a Swedish setting. LÄS MER

  4. 3. Ecological impact of antibiotic treatment on human normal microflora

    Författare :Mamun-Ur Rashid; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Ceftobiprole;

    Sammanfattning : The skin and the mucosal surfaces of humans are colonized with microorganisms which are often referred as the normal microflora. There is a biological balance between the human host and the normal microflora in health. The extensive use of antibiotics in both humans and animals has caused the development of many resistant bacteria. LÄS MER

  5. 4. Survival of infectious agents and detection of their resistance and virulence factors

    Författare :Eva Tano; Åsa Melhus; Jan Sjölin; Marie-Louise Danielsson-Tham; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transportation system; swab; polymicrobial samples; Neisseria gonorrhoeae; bacteremia; exotoxins; Staphylococcus aureus; TSST-1; silver; silver resistance; wound dressing; sil genes; laundry; tumble drying; bacterial decontamination;

    Sammanfattning : In the first study, three different transport systems for bacteria were evaluated. The CLSI M40-A guideline was used to monitor the maintenance of both mono- and polymicrobial samples during a simulated transportation at room temperature that lasted 0-48 h. LÄS MER