Sökning: "central nervous system relapse"
Visar resultat 1 - 5 av 16 avhandlingar innehållade orden central nervous system relapse.
1. lmproving diagnosis of central nervous system tumours using genetic and epigenetic tools
Sammanfattning : Brain tumor diagnostics has traditionally been based on histopathology stains. The introduction of immunohistochemistry stains resulted in improved ability to classify these often devastating tumors. The understanding of molecular markers in central nervous system tumors has improved substantially in recent decades. LÄS MER
2. Clinical factors and outcome in T-cell lymphoma: a population-based perspective
Sammanfattning : The heterogeneous group of T-cell lymphomas consist mostly of aggressive diseasess, with generally unfavourable outcome compared to aggressive B-cell lymphomas following similar therapy. This thesis focus on outcome and risk factors for inferior survival, in an unselected population-based cohort of T-cell lymphoma patients. LÄS MER
3. Factors affecting the pharmacological treatment of bipolar disorder
Sammanfattning : Background: In patients with bipolar disorder, long-term treatment with mood-stabilisers is often required to prevent manic and depressive episodes. At present, our knowledge remains limited regarding factors that influence the outcomes of mood-stabiliser treatment. LÄS MER
4. Aspects on optimisation of High Dose Methotrexate treatment in children with Acute Lymphoblastic Leukaemia
Sammanfattning : Childhood Acute Lymphoblastic Leukaemia (ALL) has a unique place in the history of oncology, as it was the first cancer to be cured by drugs. It is therefore an important model upon which concepts of chemotherapy in other malignancies have been developed. Methotrexate is a major component of most contemporary childhood ALL treatment protocols. LÄS MER
5. Diffuse large B-cell lymphoma : population-based studies of relapse and cardiac complications
Sammanfattning : Diffuse large B-cell lymphoma (DLBCL) is an aggressive life-threatening disease, but it is often possible to cure with immunochemotherapy. Not responding to primary treatment or having a relapse is associated with poor prognosis. However, it has not been well described how large the proportion of patients with relapsed/refractory disease is. LÄS MER