Sökning: "cellular receptor"
Visar resultat 6 - 10 av 751 avhandlingar innehållade orden cellular receptor.
6. Ubiquitination and Receptor Endocytosis
Sammanfattning : Protein ubiquitination is an evolutionary conserved mechanism that controls a wide variety of cellular functions. Polyubiquitinated proteins are generally degraded in the proteasome, whereas monoubiquitination controls various other cellular processes, including endocytosis and endosomal sorting. LÄS MER
7. Molecular Mechanism of Growth Hormone - Involvement of Janus Kinase 2, Insulin Receptor Substrate-1 and -2 and Phosphatidylinositol 3-Kinase In the Acute Insulin-Like Effects of Growth Hormone In Primary Rat Adipocytes
Sammanfattning : Originally studying the molecular mechanisms for the insulin-like effects of growth hormone (GH), lipogenesis and antilipolysis, in isolated rat adipocytes we found that the GH receptor (GHR) was tyrosine phosphorylated in response to GH in cells that were responsive to these effects. Then, as Janus kinase 2 (JAK2) was described as a GH-stimulated and GHR-associated tyrosine kinase, we found that JAK2 was tyrosine phosphorylated in response to GH in responsive cells. LÄS MER
8. The prostanoid FP receptor and uveoscleral outflow : A study of FP receptor expression and functions in the eye
Sammanfattning : Prostaglandin F2α is a prostanoid FP receptor agonist which acts as an intraocular pressure-lowering agent by increasing the uveoscleral outflow of aqueous humour through the ciliary muscle. The aim of this, thesis was to investigate possible mechanisms of the increased uveoscleral outflow induced by prostaglandin F2α and its analogue latanoprost acid. LÄS MER
9. Molecular Pharmacology and Structure Function Modelling of the Leukotriene B4 Receptor BLT1
Sammanfattning : Leukotrienes are membrane derived bioactive lipids that play an important role in immune responses by initiating and maintaining the inflammatory responses. Leukotriene B4 (LTB4) released at the site of an inflammatory response attracts, activates and prolongs the life of leukocytes and lymphocytes. LÄS MER
10. Adenosine receptor/dopamine receptor interactions : molecular and biochemical aspects
Sammanfattning : The dopamine receptors have been shown to be involved in a variety of higher brain functions, such as motor control, cognition and affective states. Agonist and antagonists of dopamine receptors are widely used to treat disorders such as Parkinson's disease and schizophrenia, respectively. LÄS MER