Sökning: "cellular immunology"

Visar resultat 1 - 5 av 135 avhandlingar innehållade orden cellular immunology.

  1. 1. Immune defense reactions in freshwater crayfish : Cellular components

    Författare :Charlotta Ekblom; Irene Söderhäll; Kallaya Sritunyalucksana-Dangtip; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; crustaceans; hemocytes; immunity; crayfish; proteomics; transcriptomics; Biology with specialization in Comparative Physiology; Biologi med inriktning mot jämförande fysiologi;

    Sammanfattning : The freshwater signal crayfish, Pacifastacus leniusculus, is a well-established model for studying the immune system of invertebrates. Many important discoveries have been made in this species, among others related to the clotting reaction, hematopoiesis, the prophenoloxidase activating system, the functions of crustacean immune cells, and pathogen recognition. LÄS MER

  3. 2. Molecular and cellular mechanisms in the development of IDDM in non-obese diabetic mice

    Författare :Cecilia Rietz; Inger Lundkvist; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; immunologi; Immunology;

    Sammanfattning : Insulin dependent diabetes mellitus (IDDM) is a disease caused by autoimmune destruction of the insulin producing b cells in the pancreas. The leukocytic infiltration into the b cell islets preceding disease is called insulitis. LÄS MER

  4. 3. Experimental radioimmunotherapy and effector mechanisms

    Författare :David Eriksson; Torgny Stigbrand; Eva Forsell-Aronsson; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; radioimmunotherapy; apoptosis; mitotic catastrophe; caspases; cell cycle disturbances; combination treatment.; Immunology; Immunologi;

    Sammanfattning : Radioimmunotherapy is becoming important as a new therapeutic strategy for treatment of tumour diseases. Lately monoclonal antibodies tagged with radionuclides have demonstrated encouraging results in treatment of hematological malignancies. The progress in treatment of solid tumours using radioimmunotherapy, however, has been slow. LÄS MER

  5. 4. The PD-1 pathway and the complement system in systemic lupus erythematosus

    Författare :Helga Kristjánsdóttir; Marta E Alarcón-Riquelme; Kristján Steinsson; Tom W J Huizinga; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; SLE; autoimmune diseases; PD-1; C4AQ0; low MBL; multicase family; Immunology; Immunologi; medicinsk genetik; Medical Genetics;

    Sammanfattning : Autoimmune diseases occur in up to 3-5% of the general population and represent a diverse collection of diseases with regards to clinical manifestations. The unifying factor of autoimmune diseases is tissue and organ damage as a result of an immune response mounted against self-antigens. LÄS MER

  7. 5. The mast cell transcriptome and the evolution of granule proteins and Fc receptors

    Författare :Srinivas Akula; Lars Hellman; Sandra Kleinau; Arne Egesten; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mast cell; Fc receptors; Granule serine protease; Evolution and transcriptome.; Immunologi; Immunology;

    Sammanfattning : Protection against disease-causing pathogens, known as immunity, involves numerous cells organs, tissues and their products. To able to understand the biology of immune cells (hematopoietic cells) and their role in an immune system, we have used several different methods, including transcriptome analyses, bioinformatics, production of recombinant proteins and analyses of some of them, focusing on the granule proteases by substrate phage display. LÄS MER