Sökning: "cellular immunity"

Visar resultat 11 - 15 av 182 avhandlingar innehållade orden cellular immunity.

  1. 11. HIV and SIV specific cellular immunity in macaque models

    Författare :Barbro Mäkitalo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cellular immunity is believed to be an important prerequisite for an effective HIV vaccine. Accruing data from individuals able to contain HIV-1 replication during natural infection underscores the contribution of CD8+ T cells in viral control. LÄS MER

  3. 12. Helminths and immunity against tuberculosis

    Författare :Daniel Elias; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :tuberculosis; BCG; helminths; immunomodulation; vaccination;

    Sammanfattning : The efficacy of Bacille Calmette Guerin (BCG) is low and incidence of tuberculosis (TB) is high in those areas where helminths are endemic. Protection against tuberculosis requires strong cell mediated immunity while chronic helminth infections induce responses characterized by dominant Th2 responses as well as up-regulated regulatory T cell activity. LÄS MER

  4. 13. Regulatory properties of dendritic cells and B cells in adaptive immunity

    Författare :Bengt Johansson Lindbom; Adaptivt immunförsvar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; transplantation; Immunologi; serologi; Immunology; Cellular differentiation; Cytokines; Dendritic cells; B lymphocytes; T lymphocytes;

    Sammanfattning : This thesis is based upon four original papers in which human dendritic cells (DCs) and B cells have been analyzed in terms of how they influence the character of adaptive immune responses. DCs isolated from human tonsils were found to possess a capacity to directly regulate proliferation, isotype switching, and antibody production in B cells. LÄS MER

  5. 14. Innate and adaptive cellular immunity in chronic HCV and HIV-1 infection

    Författare :Veronica D Gonzalez; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HCV; HIV-1; co-infection; adaptive immunity; innate immunity; NK cell; NKT cell; CD4 T cell; CD8 T cell; IFNalpha; ribavirin; immune activation;

    Sammanfattning : Viral infections are initially countered by an innate immune response as a first line of defence followed by an adaptive immune response. However, certain viruses successfully evade cellular immune responses and establish chronic infection. LÄS MER

  7. 15. Innate immunity in progressive multiple sclerosis

    Författare :Shahin Aeinehband; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple sclerosis is (MS) is a chronic inflammatory autoimmune disease of central nervous system (CNS) leading to demyelination, axonal damage and neurological handicap, often affecting young adults. A majority of patients with MS initiate their disease with clinical bouts and relapses, but with time convert to a progressive course with dampened signs of CNS inflammation but increasing neurological deficits. LÄS MER