Sökning: "cellular adhesion molecules"

Visar resultat 6 - 10 av 67 avhandlingar innehållade orden cellular adhesion molecules.

1. 6. Nephrin cellular trafficking and intracellular interactions

   Författare :Xiao Li Liu; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Nephrin; signal; missense mutations; trafficking.;

   Sammanfattning : Nephrin is a 180-kDa transmembrane glycoprotein belonging to the immunoglobulin family of cell adhesion molecules. Nephrin has an extracellular part with eight Ig-like motifs, one fibronectin-like domain, a transmembrane region and a short cytoplasmic tail. LÄS MER

3. 7. Role of membrane associated molecules in liver fibrosis

   Författare :Peter Rosenberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Adhesion molecules; liver fibrosis; cholestasis; R-cadherin; N-CAM; EBP50; CFTR; cystic fibrosis; methotrexate; diabetes; over-weight; alcohol;

   Sammanfattning : The aim of the study was to evaluate the role of membrane associated proteins in tissue formation and remodeling, in normal embryogenesis and in liver disease. Molecules associated with cellular membranes provide a fundamental basis for cellular interactions during development, homeostasis and disease. LÄS MER

4. 8. Integrin Signaling in Cell Adhesion and Mechanotransduction : Regulation of PI3K, AKT, and ROS

   Författare :Kathrin Stephanie Zeller; Staffan Johansson; Kristofer Rubin; John Couchman; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; integrin; ROS; PI3K; AKT; mechanosignaling; actin polymerization; spreading;

   Sammanfattning : Integrins are a family of conserved cell surface receptors found throughout the animal kingdom. They comprise 24 dimers in mammals, and regulate a number of processes including cell survival, differentiation, and migration. LÄS MER

5. 9. Effect of surface characteristics on cellular adherence and activity

   Författare :Marjan Dorkhan; Malmö högskola; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bacteria; microbial biofilm; dental implant; streptococci; oral bacteria; salivary pellicle; early colonizers; titanium oxide; microbial activity; oral keratinocytes; gingival fibroblasts; cell attachment; surface modification; anodic oxidation; anatase;

   Sammanfattning : Ersättning av förlorade tänder med tandimplantat är numera en vanlig behandlingsmetod med generellt goda resultat. Antalet implantatsystem på den internationella marknaden har ökat kraftigt under senare år. LÄS MER

7. 10. Protein and Cell Interactions with Nanostructured Surfaces

   Författare :Emma Westas; Chalmers tekniska högskola; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; bacteria; titanium dioxide; implant associated infections; metabolomics; cellular interactions; hydroxyapatite; immune complement activation; silica; nanoparticles; photocatalysis; protein adsorption; Nanostructured implants;

   Sammanfattning : A great challenge of today’s implant development is to construct a surface that promotes tissue integration and avoids bacterial colonization. To avoid implant related infections, many argue that a surface promoting strong cell adhesion and tissue integration in favour for bacterial adhesion would solve the problem, the so-called race for the surface concept. LÄS MER