Sökning: "cellforskning"

Visar resultat 16 - 19 av 19 avhandlingar innehållade ordet cellforskning.

1. 16. Adhesion Dependent Signals : Cell Survival, Receptor Crosstalk and Mechanostimulation

   Författare :Anjum Riaz; Staffan Johansson; Bengt Hallberg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Integrins; Signal transduction; Protein kinase B; Akt; PI3K; Heparanase; ROS; Mechanosignalling; Molekylär cellbiologi; Molecular Cellbiology; Biology with specialization in Molecular Cell Biology; Biologi med inriktning mot molekylär cellbiologi; Cellforskning; Cell Research;

   Sammanfattning : The integrin family of cell surface receptors is evolutionary conserved and found in all multicellular animals. In humans 8-alpha and 18-beta integrins are non-covalently associated into 24 dimers. Integrins mediate cell-extracellular matrix and cell-cell interactions and participate in cell signalling. LÄS MER

3. 17. Stem cells for nerve repair and prevention of muscle atrophy

   Författare :Dominique Schaakxs; Paul Kingham; Mikael Wiberg; Daniel Kalbermatten; Christine Radtke; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipose stem cells; biomaterial; muscle; nerve injury; neuromuscular junction; regeneration; cell research; cellforskning; Medical Cell Biology; medicinsk cellbiologi;

   Sammanfattning :   Peripheral nerve injury (PNI) is common and despite modern microsurgical techniques of repair, functional restoration is always incomplete. This results in impaired sensation and reduced motor function alongside pain and cold intolerance. LÄS MER

4. 18. Cytoskeletal filament systems : assembly, regulation, and interplay in mammalian cells

   Författare :Mikael E Sellin; Martin Gullberg; Jeremy Thorner; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cell research; cellforskning;

   Sammanfattning : The cell represents the basic unit of structure and function for all life. The interior of a eukaryotic cell is organized by an extensive array of protein filaments – collectively referred to as the cytoskeleton. These filaments serve diverse essential functions, e.g. LÄS MER

5. 19. Targeting Gb3 and apoptosis-related proteins to overcome cisplatin resistance

   Författare :Andreas Tyler; Kjell Grankvist; Simon Ekman; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cisplatin resistance; exosomes; gb3; HSP70; the Bcl-2 family; cell research; cellforskning; Medical Cell Biology; medicinsk cellbiologi; onkologi; Oncology;

   Sammanfattning : Background Cisplatin is used for treatment of malignant pleural mesothelioma (MPM) and non-small cell lung cancer (NSCLC) but treatment with cisplatin often leads to acquired resistance to cisplatin, resulting in poor patient survival. Globotriaosylceramide (Gb3) and multidrug resistance protein 1 (MDR1) have been associated with cisplatin resistance. LÄS MER